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1990年至2003年波兰的腮腺炎;流行病学与抗体流行情况

Mumps in Poland since 1990 to 2003; epidemiology and antibody prevalence.

作者信息

Janaszek-Seydlitz Wieslawa, Bucholc Bozena, Gorska Paulina, Slusarczyk Janusz

机构信息

Department of Sera and Vaccine Evaluation, National Institute of Hygiene, Chocimska 24, Warsaw, Poland.

出版信息

Vaccine. 2005 Apr 15;23(21):2711-6. doi: 10.1016/j.vaccine.2004.11.050.

Abstract

The annual incidence of mumps in Poland over the period 1990-2003 was 45-570 per 100,000 population with the epidemic peak every 4-5 years. Till 2003, mumps vaccination has not been included in the part of National Immunisation Program in Poland that comprises the obligatory vaccinations. However, mumps vaccination was recommended by National Health Authority for children at the second year of life and it could be obtained privately. The proportion of vaccinated children has increased by 50% in last years. It has influenced on decreasing of number of notified mumps cases in Poland, on lengthening of inter-epidemic period as well as on drift of infections towards older groups of children. The results of serological survey carried out on 1390 serum samples have indicated, that the proportion of positive serum samples (>11 VE/ml) was only 24.1% for children aged 1-4 years, 45.4% for children aged 5-9 years, 72.5% for age group 10-14 years, and over 85% for persons aged 15-30 years. Epidemiological data and the high proportion of individuals with negative titres of specific mumps IgG antibodies justify the need of introduction of obligatory mass immunisation against mumps in Poland.

摘要

1990年至2003年期间,波兰腮腺炎的年发病率为每10万人45 - 570例,每4 - 5年出现一次流行高峰。直到2003年,腮腺炎疫苗接种尚未纳入波兰国家免疫规划中包含的强制性疫苗接种部分。然而,国家卫生当局建议对两岁儿童接种腮腺炎疫苗,且可通过私人途径获得。近年来,接种疫苗的儿童比例增加了50%。这对波兰腮腺炎病例报告数量的减少、流行间期的延长以及感染向大龄儿童群体的转移都产生了影响。对1390份血清样本进行的血清学调查结果表明,1 - 4岁儿童中阳性血清样本(>11 VE/ml)的比例仅为24.1%,5 - 9岁儿童为45.4%,10 - 14岁年龄组为72.5%,15 - 30岁人群超过85%。流行病学数据以及特定腮腺炎IgG抗体滴度为阴性的个体比例较高,证明了波兰有必要引入强制性的腮腺炎群体免疫。

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