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美国海军哮喘健康监测:9185484人年的经验

Health surveillance for asthma in the US Navy: experience of 9,185,484 person-years.

作者信息

Gunderson E K Eric, Garland Cedric F, Gorham Edward D

机构信息

Longitudinal Studies and Health Sciences Program, Naval Health Research Center, San Diego, CA, USA.

出版信息

Ann Epidemiol. 2005 Apr;15(4):310-5. doi: 10.1016/j.annepidem.2004.08.004.

Abstract

PURPOSE

To measure trends and demographic risk factors for hospitalization for asthma.

METHODS

Time trends and demographic risk factors, for hospitalized asthma (1CD-9-CM Code 493) were analyzed by measuring age-specific and age-adjusted first hospitalization rates in a defined population of active-duty enlisted members of the US Navy worldwide during 1980-1999, consisting of 9,185,484 person-years.

RESULTS

There were 3911 patients first hospitalized for asthma, including 2916 men and 995 women. The age-adjusted incidence rate of first hospitalization for asthma was three times higher in women than men, 110 per 100,000 person-years (95% confidence interval [CI], 104-117), compared with 35 per 100,000 person-years (95% CI, 33-37), respectively (p < 0.0001). The rate in black women was twice as high as in white women, 186 per 100,000 person-years, compared with 99 per 100,000 person-years, respectively (p < 0.001). The rate in black men was higher than in white men, 45 per 100,000, compared with 34 per 100,000 (p < 0.001). Age-adjusted rates in women doubled from 73 per 100,000 in 1980-1983 to 159 in 1997-1999 (p for trend < 0.01), while those in men remained stable.

CONCLUSIONS

Age-adjusted incidence rates of first hospitalization for asthma were three times as high in women as in men, and doubled during the period between 1980 and 1999. The rates in black women were twice as high as in white women. The reasons are unknown.

摘要

目的

测量哮喘住院治疗的趋势及人口统计学风险因素。

方法

通过测量1980 - 1999年期间全球美国海军现役入伍人员这一特定人群中按年龄划分及年龄调整后的首次住院率,分析住院哮喘(国际疾病分类第九版临床修订本代码493)的时间趋势和人口统计学风险因素,该人群总计9,185,484人年。

结果

共有3911例患者首次因哮喘住院,其中男性2916例,女性995例。哮喘首次住院的年龄调整发病率女性是男性的三倍,分别为每10万人年110例(95%置信区间[CI],104 - 117)和每10万人年35例(95% CI,33 - 37)(p < 0.0001)。黑人女性的发病率是白人女性的两倍,分别为每10万人年186例和每10万人年99例(p < 0.001)。黑人男性的发病率高于白人男性,分别为每10万人年45例和每10万人年34例(p < 0.001)。女性的年龄调整发病率从19八十年代的每10万人年73例翻倍至1997 - 1999年的159例(趋势p < 0.01),而男性的发病率保持稳定。

结论

哮喘首次住院的年龄调整发病率女性是男性的三倍,且在1980年至1999年期间翻倍。黑人女性的发病率是白人女性的两倍。原因不明。

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