Sukhija Rishi, Aronow Wilbert S, Yalamanchili Kiran, Lee Jooyun, McClung John A, Levy James A, Belkin Robert N
Department of Medicine, Cardiology Division, Westchester Medical Center/New York Medical College, Valhalla, NY 10595, USA.
Cardiology. 2005;103(3):156-7. doi: 10.1159/000084585. Epub 2005 Mar 21.
Acute pulmonary embolism (PE) may result in right ventricular (RV) pressure overload with a dilated RV which can be diagnosed by two-dimensional echocardiography.
A retrospective analysis was performed in 190 unselected patients who had acute PE documented by contrast-enhanced spiral computed tomographic scanning. The 190 patients included 104 women and 86 men, mean age 58 +/- 15 years.
RV dilatation was present in 45 of 70 patients (64%) with bilateral PE, in 19 of 120 patients (16%) without bilateral PE, in 42 of 47 patients (89%) with main pulmonary artery embolism, in 34 of 84 patients (40%) with lobar PE, in 16 of 70 patients (23%) with segmental PE and in 6 of 36 patients (17%) with subsegmental PE; p < 0.001 comparing bilateral with no bilateral PE and main pulmonary artery embolism with no main pulmonary artery embolism, with lobar, segmental and subsegmental PE; p < 0.025 comparing lobar with segmental PE, and p < 0.02 comparing lobar with subsegmental PE.
The prevalence of RV dilatation is highest in patients with main pulmonary artery embolism or bilateral pulmonary artery embolism; furthermore, the prevalence of RV dilatation is higher in patients with lobar PE than in patients with segmental or subsegmental PE.
急性肺栓塞(PE)可能导致右心室(RV)压力负荷过重,右心室扩张,这可通过二维超声心动图诊断。
对190例经对比增强螺旋计算机断层扫描确诊为急性肺栓塞的未选择患者进行回顾性分析。190例患者中,女性104例,男性86例,平均年龄58±15岁。
双侧肺栓塞的70例患者中有45例(64%)出现右心室扩张,无双侧肺栓塞的120例患者中有19例(16%)出现右心室扩张,主肺动脉栓塞的47例患者中有42例(89%)出现右心室扩张,肺叶性肺栓塞的84例患者中有34例(40%)出现右心室扩张,节段性肺栓塞的70例患者中有16例(23%)出现右心室扩张,亚段性肺栓塞的36例患者中有6例(17%)出现右心室扩张;双侧与非双侧肺栓塞、主肺动脉栓塞与非主肺动脉栓塞、肺叶性、节段性和亚段性肺栓塞比较,p<0.001;肺叶性与节段性肺栓塞比较,p<0.025,肺叶性与亚段性肺栓塞比较,p<0.02。
主肺动脉栓塞或双侧肺动脉栓塞患者右心室扩张的发生率最高;此外,肺叶性肺栓塞患者右心室扩张的发生率高于节段性或亚段性肺栓塞患者。