Schmitt Jochen, Wozel Gottfried
Department of Dermatology, University Hospital Carl Gustav Carus, Technical University Dresden, DE-01307 Dresden, Germany.
Dermatology. 2005;210(3):194-9. doi: 10.1159/000083509.
Chronic plaque-type psoriasis is a major dermatosis, but a significant question is still unanswered: What defines severity in chronic plaque-type psoriasis? While objective assessments like the Psoriasis Area and Severity Index (PASI) have frequently been used in clinical trials, quality of life (QOL) questionnaires are currently becoming more and more popular.
This article summarizes the most important objective and subjective measurements of severity in psoriasis. For every dermatologist it is critically important to distinguish between severe psoriasis and psoriasis that severely affects QOL. Even if the PASI also has disadvantages, it is the most adequate instrument available to evaluate severity in plaque-type psoriasis.
We provide reasons why PASI >12 defines severe, PASI 7-12 moderate and PASI <7 mild chronic plaque-type psoriasis.
慢性斑块型银屑病是一种主要的皮肤病,但一个重要问题仍未得到解答:如何定义慢性斑块型银屑病的严重程度?虽然像银屑病面积和严重程度指数(PASI)这样的客观评估在临床试验中经常被使用,但生活质量(QOL)问卷目前正变得越来越受欢迎。
本文总结了银屑病严重程度最重要的客观和主观测量方法。对于每位皮肤科医生来说,区分重度银屑病和严重影响生活质量的银屑病至关重要。即使PASI也有缺点,但它是评估斑块型银屑病严重程度最适用的工具。
我们阐述了为何PASI>12定义为重度、PASI 7 - 12为中度、PASI<7为轻度慢性斑块型银屑病的原因。