Colombo Giorgio Lorenzo, Caruggi Mauro, Serra Giulio, Vinci Marta
S.A.V.E. Studi Analisi Valutazioni Economiche, Milano.
Recenti Prog Med. 2005 Jan;96(1):7-15.
This study aims to measure quality of life and treatment costs of patients with acute pain due to osteoarticular diseases;2 to asses associations between pain, quality of life and treatment costs from NHS' perspective.
Observational, multicentric study; patients of both gender were enrolled sequentially from March to July 2002 and observed for 30 days. Type of pain was assessed by a McGill Pain Questionnaire, while degree of severity was measured by VAS (Visual Analogue Scale) ranging from 0 (no pain) to 10 (very severe pain). Quality of life was assessed by EQ-5D (EuroQol/Quality of Life in Europe-5 Dimensions).
188 patients matched by gender and age in to four group: male < or =65 years (51), female < or =65 years (59), male > 65 years (42), female > 65 years (36). Male's age ranged from 36 to 88 years, while female's ranged from 31 to 87 years. Groups differ for type of pain. Cost after enrollment (48.99 Euro) is due for about 60% to diagnostic examinations, while pharmacological therapies account for only 17.64 Euro. Mean score of EQ-5D shows a low level of utility (0.265) that reflects a rather law quality of life. Patient older than 65 years had lower score than patient of the same gender but younger. Differences are significant in the dimension anxiety/depression that afflicts women and older patients.
This study valued utility of patients with non oncological acute pain in Italy and health cost of diagnostic and therapeutic path faced by patients.
本研究旨在衡量骨关节炎疾病所致急性疼痛患者的生活质量和治疗成本;从英国国家医疗服务体系(NHS)的角度评估疼痛、生活质量和治疗成本之间的关联。
观察性多中心研究;2002年3月至7月按顺序纳入男女患者并观察30天。疼痛类型通过麦吉尔疼痛问卷进行评估,严重程度通过视觉模拟量表(VAS)测量,范围从0(无疼痛)至10(非常严重疼痛)。生活质量通过欧洲五维健康量表(EQ - 5D)进行评估。
188名患者按性别和年龄匹配分为四组:男性≤65岁(51例),女性≤65岁(59例),男性>65岁(42例),女性>65岁(36例)。男性年龄范围为36至88岁,女性年龄范围为31至87岁。各组疼痛类型不同。入组后的费用(48.99欧元)约60%用于诊断检查,而药物治疗仅占17.64欧元。EQ - 5D的平均得分显示效用水平较低(0.265),这反映出生活质量相当低。65岁以上患者的得分低于同性别但年龄较小的患者。在困扰女性和老年患者的焦虑/抑郁维度上差异显著。
本研究评估了意大利非肿瘤性急性疼痛患者的效用以及患者所面临的诊断和治疗路径的健康成本。