Goodacre S, Mason S, Arnold J, Angelini K
Northern General Hospital, Sheffield, United Kingdom.
Ann Emerg Med. 2001 Oct;38(4):369-76. doi: 10.1067/mem.2001.118010.
We sought to measure psychologic morbidity and health-related quality of life among patients attending the hospital with acute chest pain both at presentation and 1 month after rigorous assessment for cardiac disease.
Consecutive patients undergoing assessment on the chest pain observation unit of a large, urban emergency department were asked to complete 3 questionnaires: the Short Form-36 Health Survey (SF-36), the Euroqol Health Utility Questionnaire, and the Hospital Anxiety and Depression Scale. The same questionnaires were mailed 1 month later, along with a questionnaire documenting subsequent pain and reassurance.
At enrollment (n=166), 32 (19%) participants (95% confidence interval [CI] 15% to 26%) were experiencing moderate levels of anxiety, and 21 (13%, 95% CI 8% to 19%) were experiencing moderate levels of depression. Health utility and all SF-36 dimensions of quality of life were substantially below age-adjusted normal values. One month after assessment (n=110), only the Pain dimension score of SF-36 had significantly improved. Most scores were unchanged, and the Physical Role and Mental Health dimension scores of SF-36 had significantly deteriorated. Seventy (64%) patients (95% CI 54% to 72%) had further pain after discharge. Despite these findings, 98 (86%) patients (95% CI 78% to 91%) responded that their assessment was "completely reassuring" or "quite reassuring."
Patients with acute, undifferentiated chest pain have substantial psychologic morbidity and impairment of quality of life. Although patients respond that they are reassured by chest pain observation unit assessment, anxiety and depression remain prevalent and quality of life remains impaired 1 month after assessment.
我们试图测量因急性胸痛到医院就诊的患者在就诊时以及经过心脏病严格评估1个月后的心理发病率和与健康相关的生活质量。
在一家大型城市急诊科胸痛观察病房接受评估的连续患者被要求完成3份问卷:简短健康调查问卷(SF-36)、欧洲生活质量健康效用问卷和医院焦虑抑郁量表。1个月后,同样的问卷被邮寄出去,同时还有一份记录后续疼痛和安心情况的问卷。
在入组时(n = 166),32名(19%)参与者(95%置信区间[CI]为15%至26%)存在中度焦虑,21名(13%,95%CI为8%至19%)存在中度抑郁。健康效用和SF-36生活质量的所有维度均显著低于年龄校正后的正常值。评估1个月后(n = 110),只有SF-36的疼痛维度得分有显著改善。大多数得分未变,SF-36的身体功能和心理健康维度得分显著恶化。70名(64%)患者(95%CI为54%至72%)出院后仍有进一步疼痛。尽管有这些发现,但98名(86%)患者(95%CI为78%至91%)表示他们的评估“完全安心”或“相当安心”。
急性、未分化胸痛患者存在严重的心理发病率和生活质量受损情况。尽管患者表示胸痛观察病房的评估让他们安心,但焦虑和抑郁仍然普遍存在,且评估1个月后生活质量仍受损。