Schönhofer B, Bundschu H D, Wolf K, Grehn S
Medizinische Klinik, Caritas-Krankenhaus Bad Mergentheim.
Med Klin (Munich). 1992 Apr 15;87(4):172-8.
Between March 1990 and March 1991, in a prospective study, 100 patients (53 men, 47 women, median age 61.5 years) with suspected deep venous thrombosis of the lower extremities, colour duplex ultrasonography (CDU) (Ultramark 9, ATL) were investigated using the slow-flow technique. The CDU findings obtained for the external iliac vein (distal segment), the common femoral, the superficial femoral and popliteal veins, together with those of the veins of the lower extremity, were compared with the results of phlebography, which is considered to be the gold standard for this type of investigation. The sensitivity/specificity of CDU in diagnosing deep venous thrombosis was, from proximal to distal: 95.4%/100%, 100%/99%, 96.8%/97.1%, 98.5%/95.5% and 96.3%/98%. Fibrinolytic therapy (ultra high-dose short-term therapy: n = 16 patients; conventional fibrinolytic therapy: n = 4 patients) was indicated in 20 patients. In this group of patients identical results were obtained with CDU and ascending phlebography. Our experience shows CDU to be a supplementary diagnostic procedure to real-time B mode ultrasonic imaging in the establishment of the primary diagnosis, and to be superior to it in the follow-up evaluation of the results of fibrinolytic treatment. Both in the establishment of the primary diagnosis and follow-up of thrombosis of the deep leg and pelvic veins, CDU is the equal of phlebography. The advantage of the latter is in the documentation of the entire venous system and staging of post-thrombotic syndrome.
1990年3月至1991年3月期间,在一项前瞻性研究中,对100例疑似下肢深静脉血栓形成的患者(53例男性,47例女性,中位年龄61.5岁)使用慢流技术进行了彩色双功超声检查(CDU)(Ultramark 9,ATL)。将髂外静脉(远段)、股总静脉、股浅静脉和腘静脉以及下肢静脉的CDU检查结果与静脉造影结果进行比较,静脉造影被认为是这类检查的金标准。CDU诊断深静脉血栓形成的敏感性/特异性,从近端到远端依次为:95.4%/100%、100%/99%、96.8%/97.1%、98.5%/95.5%和96.3%/98%。20例患者接受了溶栓治疗(超高剂量短期治疗:n = 16例患者;传统溶栓治疗:n = 4例患者)。在这组患者中,CDU和上行静脉造影得到了相同的结果。我们的经验表明,在建立初步诊断时,CDU是实时B型超声成像的辅助诊断方法,在溶栓治疗结果的随访评估中优于实时B型超声成像。在深腿部和盆腔静脉血栓形成的初步诊断及随访中,CDU与静脉造影效果相当。后者的优势在于能记录整个静脉系统并对血栓形成后综合征进行分期。