丘疹型蕈样肉芽肿：蕈样肉芽肿早期的一种新临床变体。
Papular mycosis fungoides: a new clinical variant of early mycosis fungoides.
作者信息
Kodama Kazuo, Fink-Puches Regina, Massone Cesare, Kerl Helmut, Cerroni Lorenzo
机构信息
Department of Dermatology, Medical University of Graz, Graz, Austria.
出版信息
J Am Acad Dermatol. 2005 Apr;52(4):694-8. doi: 10.1016/j.jaad.2004.12.018.
BACKGROUND
Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. In early stages of the disease many different clinicopathologic variants have been observed.
OBSERVATION
We report 6 patients with early manifestations of MF characterized by the sole presence of papules which, unlike the papules of lymphomatoid papulosis, did not show a tendency for spontaneous resolution. Histologic examination confirmed the diagnosis of MF in all cases. Immunohistochemical staining for CD30 was negative in all cases. Follow-up data showed the nonaggressive behavior of the disease, confirming that the lesions were not manifestations of advanced MF.
CONCLUSION
Papular MF is a new variant of early MF characterized by the presence of papules in the absence of more conventional early lesions (patches) of the disease. This variant should be added to the long list of clinicopathologic subtypes of MF.
背景
蕈样肉芽肿（MF）是最常见的皮肤T细胞淋巴瘤类型。在疾病的早期阶段，已观察到许多不同的临床病理变异型。
观察
我们报告了6例MF早期表现的患者，其特征为仅存在丘疹，与淋巴瘤样丘疹病的丘疹不同，这些丘疹没有自发消退的倾向。组织学检查在所有病例中均确诊为MF。所有病例CD30免疫组化染色均为阴性。随访数据显示该疾病行为不具侵袭性，证实这些病变并非晚期MF的表现。
结论
丘疹型MF是早期MF的一种新变异型，其特征是存在丘疹，而无该疾病更常见的早期损害（斑片）。这种变异型应添加到MF临床病理亚型的众多列表中。
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