Jedrzejczak Piotr, Taszarek-Hauke Grazyna, Derwich Krzysztof, Depa Magdalena, Pawelczyk Leszek
Klinika Niepłodności i Endokrynologii Rozrodu Katedry Ginekologii i Połoznictwa Akademii Medycznej w Poznaniu.
Przegl Lek. 2004;61(10):1028-30.
In this prospective study different semen parameters of fertile smokers were compared with fertile non-smokers. 58 men with proven fertility (17 smokers and 41 non-smokers) at the same age were evaluated. Smokers had significantly less spermatozoa with motility grade A (p<0.01), B (p<0.05), and C (p<0.05), and more abnormal forms in the ejaculate (p< 0.001). The percentage of sperm with head defects (p<0.05) and cytoplasmic droplets (p<0.001) were also significantly higher in smokers. No differences were found in the assessment of semen volume, total sperm count, hypoosmotic swelling test, induced acrosomal reaction and acidic aniline blue staining test between two groups (p>0.05). However the concentration of leukocytes in semen was significantly higher in smokers (p<0.001), which can suggests oxidative imbalance in the ejaculates of these men. Our data demonstrate that cigarette smoking is associated with reduced semen quality which could worsen fertilizing potential in fertile men.
在这项前瞻性研究中，对有生育能力的吸烟者和不吸烟者的不同精液参数进行了比较。对58名年龄相同且已证实具有生育能力的男性（17名吸烟者和41名不吸烟者）进行了评估。吸烟者中，A级（p<0.01）、B级（p<0.05）和C级（p<0.05）活力的精子明显较少，且射精中的异常形态更多（p<0.001）。吸烟者中头部缺陷精子的百分比（p<0.05）和细胞质滴的百分比（p<0.001）也显著更高。两组之间在精液量、总精子数、低渗肿胀试验、诱导顶体反应和酸性苯胺蓝染色试验的评估中未发现差异（p>0.05）。然而，吸烟者精液中的白细胞浓度显著更高（p<0.001），这可能表明这些男性射精中的氧化失衡。我们的数据表明，吸烟与精液质量下降有关，这可能会降低有生育能力男性的受精潜力。
