Ruthazer Edward S
Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Neuron. 2005 Mar 24;45(6):825-8. doi: 10.1016/j.neuron.2005.03.008.
The receptive field properties of neurons in the developing brain can in many cases be remarkably similar to those of adult neurons. This raises the question of why these same neurons need the capacity for such impressive developmental plasticity, most clearly demonstrated by the rewiring that occurs in response to sensory deprivation. The roles of developmental neuronal plasticity in the assimilation of neurons into a larger network, including temporal and cross-modal integration, are discussed.
在发育中的大脑中,神经元的感受野特性在许多情况下与成年神经元的感受野特性非常相似。这就提出了一个问题:为什么这些相同的神经元需要具备如此显著的发育可塑性,最明显的表现是在感觉剥夺后发生的神经回路重连。本文讨论了发育性神经元可塑性在神经元融入更大网络过程中的作用,包括时间整合和跨模态整合。