Han Beth, Phillips Caroline, Ferrucci Luigi, Bandeen-Roche Karen, Jylha Marja, Kasper Judith, Guralnik Jack M
National Center for Health Statistics, Hyattsville, MD, USA.
Gerontologist. 2005 Apr;45(2):216-21. doi: 10.1093/geront/45.2.216.
Our study assessed whether change in self-rated health is a stronger predictor of mortality than baseline self-rated health and the most recent self-rated health (prior to death or loss to follow-up) among disabled older women.
The Women's Health and Aging Study examined disabled older women at baseline and every 6 months for 3 years. During the follow-up period, 253 out of the 905 examined participants died. Cox regression models with time-dependent covariates were used.
After baseline characteristics were adjusted for, baseline self-rated health was not related to mortality. After covariates at the most recent observation and covariates measured only at baseline were controlled for, the most recent self-rated health was not associated with mortality either. After time-dependent covariates and covariates measured only at baseline were adjusted for, decline in self-rated health was significantly associated with increased mortality.
Change in self-rated health is a stronger predictor of mortality than self-rated health at baseline and at the most recent observation. Older women with "fair" health are worse off if they are on a declining health trajectory than if their "fair" health is stable. Family caregivers and clinicians need to closely monitor change in self-rated health among disabled older women.
我们的研究评估了在残疾老年女性中,自我评估健康状况的变化是否比基线自我评估健康状况以及最近一次自我评估健康状况(在死亡或失访之前)更能预测死亡率。
妇女健康与衰老研究在基线时对残疾老年女性进行检查,并在3年中每6个月检查一次。在随访期间,905名接受检查的参与者中有253人死亡。使用了带有时间依存性协变量的Cox回归模型。
在对基线特征进行调整后,基线自我评估健康状况与死亡率无关。在对最近一次观察时的协变量以及仅在基线时测量的协变量进行控制后,最近一次自我评估健康状况也与死亡率无关。在对时间依存性协变量和仅在基线时测量的协变量进行调整后,自我评估健康状况的下降与死亡率增加显著相关。
自我评估健康状况的变化比基线和最近一次观察时的自我评估健康状况更能预测死亡率。健康状况为“一般”的老年女性,如果其健康状况呈下降趋势,情况会比其“一般”健康状况稳定时更糟。家庭护理人员和临床医生需要密切监测残疾老年女性自我评估健康状况的变化。