Hirota Tatsuya, Yamagami Takuji, Tanaka Osamu, Iida Shigeharu, Kato Takeharu, Nishimura Tsunehiko
Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo, Kyoto, 602-8566, Japan.
J Vasc Interv Radiol. 2005 Apr;16(4):471-6. doi: 10.1097/01.RVI.0000152387.43037.33.
The stroke rate after left subclavian arterial port-catheter placement was compared in two groups: one with minimal redundancy of the catheter and one with pronounced redundancy in the aortic arch designed to minimize the likelihood of catheter dislocation.
One hundred forty-eight patients (102 men, 46 women; age range, 26-83 years; mean age, 64.3 years) with inoperable advanced liver cancers underwent percutaneous implantation of port-catheter systems via the left subclavian artery. In 33 patients, a pronounced redundancy of the catheter was intentionally looped in the aortic arch. Redundancy was intentionally avoided in the remaining 115 patients. The rates of brain infarction complications in these two groups were retrospectively compared.
Among the 33 patients with pronounced redundant catheter looping, brain infarctions occurred in four cases (12.1%). In contrast, brain infarctions occurred in only three of the 115 patients with minimal redundant catheter looping (2.6%). The frequency of brain infarction complications was significantly higher in the patients with pronounced redundant catheter looping in the aortic arch than in patients with minimal pronounced redundant catheter looping (P = .044, Fisher exact test).
Catheter redundancy in the aortic arch increases the risk of stroke in patients undergoing implantation of port-catheter systems via a left subclavian arterial approach for repeated hepatic arterial infusion chemotherapy.
比较两组患者左锁骨下动脉植入端口导管系统后的卒中发生率:一组导管冗余度最小,另一组在主动脉弓处有明显冗余以尽量降低导管移位的可能性。
148例无法手术切除的晚期肝癌患者(102例男性,46例女性;年龄范围26 - 83岁;平均年龄64.3岁)经左锁骨下动脉接受经皮植入端口导管系统。33例患者中,导管在主动脉弓处有意形成明显冗余的袢。其余115例患者有意避免导管冗余。回顾性比较这两组患者脑梗死并发症的发生率。
在33例导管有明显冗余袢的患者中,4例发生脑梗死(12.1%)。相比之下,115例导管冗余度最小的患者中仅有3例发生脑梗死(2.6%)。主动脉弓处导管有明显冗余的患者脑梗死并发症的发生率显著高于导管冗余度最小的患者(P = .044,Fisher精确检验)。
对于经左锁骨下动脉途径植入端口导管系统以进行重复肝动脉灌注化疗的患者,主动脉弓处的导管冗余会增加卒中风险。