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妊娠期间的多形性胶质母细胞瘤

Glioblastoma multiforme in pregnancy.

作者信息

Mackenzie Andrew P, Levine Gary, Garry David, Figueroa Reinaldo

机构信息

Department of Obstetrics and Gynecology, Winthrop University Hospital, Mineola, New York 11501, USA.

出版信息

J Matern Fetal Neonatal Med. 2005 Jan;17(1):81-3. doi: 10.1080/14767050400028709.

Abstract

Brain tumors in pregnancy are uncommon occurrences. A 48-year-old female at 36 2/7 weeks of gestation presented with right-sided weakness and parasthesias, a facial droop, and an unsteady gait. Brain imaging studies revealed a left-sided parietal lesion impinging upon the lateral ventricle. She underwent a cesarean delivery and then a craniotomy with resection of a glioblastoma multiforme two days later. Despite treatment with radiation and chemotherapy, she died nine months later. Glioblastoma multiforme is a rare diagnosis during pregnancy which may present as a neurologic emergency.

摘要

妊娠期脑肿瘤并不常见。一名48岁女性,孕36又2/7周,出现右侧肢体无力和感觉异常、面部下垂及步态不稳。脑部影像学检查显示左侧顶叶病变压迫侧脑室。她接受了剖宫产,两天后又接受了开颅手术,切除多形性胶质母细胞瘤。尽管接受了放疗和化疗,她还是在九个月后去世了。多形性胶质母细胞瘤在孕期是一种罕见的诊断,可能表现为神经急症。

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