Hollingsworth M A, Batra S K, Qi W N, Yankaskas J R
Eppley Institute, University of Nebraska Medical Center, Omaha 68198-6805.
Am J Respir Cell Mol Biol. 1992 May;6(5):516-20. doi: 10.1165/ajrcmb/6.5.516.
The MUC1 mucin mRNA, for which the cDNA was previously cloned from human breast and pancreatic tissues, was found to be expressed in nasal and bronchial epithelial cell primary cultures from cystic fibrotic, atopic, and normal individuals. Sequence analysis of cDNA clones from the CF/T43 cystic fibrosis nasal epithelial cell line revealed only insignificant differences in the 3' untranslated region of the mRNA when compared with the pancreas and breast mucin cDNAs.
MUC1粘蛋白mRNA，其cDNA先前已从人乳腺和胰腺组织中克隆出来，发现在来自囊性纤维化、特应性和正常个体的鼻腔和支气管上皮细胞原代培养物中表达。对CF/T43囊性纤维化鼻上皮细胞系的cDNA克隆进行序列分析发现，与胰腺和乳腺粘蛋白cDNA相比，该mRNA的3'非翻译区仅存在微不足道的差异。
