Gruszecki Amy C, McGwin Gerald, Robinson C Andrew, Davis Gregory G
University of Alabama at Birmingham, USA.
J Forensic Sci. 2005 Mar;50(2):419-22.
The common history of drug abuse in adults with an undetermined cause of death has led us to hypothesize that chronic drug abuse increases the risk of sudden death. To begin evaluating this hypothesis, we conducted a retrospective case-control study of 61 decedents whose cause of death remained undetermined following autopsy matched one to one to a control group of pedestrians or passengers killed in motor vehicle collisions. In 21 pairs, the case subject had evidence of drug abuse but the control did not, and in 5 cases the reverse was true. Analysis showed that individuals with an undetermined cause of death are 4.2 times more likely to have evidence of drug abuse than are victims of a motor vehicle collision.
在死因不明的成年人中，药物滥用的常见病史使我们推测，长期药物滥用会增加猝死风险。为了开始评估这一假设，我们进行了一项回顾性病例对照研究，对61名死者进行了研究，这些死者在尸检后死因仍未确定，他们与在机动车碰撞事故中死亡的行人或乘客对照组进行一对一匹配。在21对中，病例组有药物滥用证据而对照组没有，在5对中情况相反。分析表明，死因不明的个体有药物滥用证据的可能性是机动车碰撞事故受害者的4.2倍。
