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前列腺癌治疗:标准管理、新选择与实验方法。

Prostate cancer therapy: standard management, new options and experimental approaches.

作者信息

Trojan Lutz, Kiknavelidze Koba, Knoll Thomas, Alken Peter, Michel Maurice Stephan

机构信息

Department of Urology, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

出版信息

Anticancer Res. 2005 Jan-Feb;25(1B):551-61.

Abstract

The management of prostate cancer is one of the core tasks for urologists today. This review focuses on therapeutic options for the curative and palliative treatment of prostate cancer. Within the area of urological competence, radical prostatectomy remains the standard procedure for the curative treatment of localised prostate cancer. Recently, interest in minimally-invasive procedures such as brachytherapy, focused ultrasound and cryotherapy has increased considerably. Established palliative treatment strategies include hormonal treatment schemes as the gold standard. Chemotherapeutic regimes are used for the hormone refractory disease. In addition to both the standard and new urological therapeutic options, promising experimental systemic strategies for the generalised disease are presented in this review.

摘要

前列腺癌的管理是当今泌尿外科医生的核心任务之一。本综述聚焦于前列腺癌根治性和姑息性治疗的治疗选择。在泌尿外科领域内,根治性前列腺切除术仍是局限性前列腺癌根治性治疗的标准手术。近来,对近距离放射疗法、聚焦超声和冷冻疗法等微创治疗的兴趣大幅增加。既定的姑息性治疗策略包括将激素治疗方案作为金标准。化疗方案用于激素难治性疾病。除了标准和新的泌尿外科治疗选择外,本综述还介绍了针对广泛性疾病有前景的实验性全身治疗策略。

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