Pauli E, Haller U, Zimmermann R
Departement Frauenheilkunde, Universitätsspital Zürich, Zürich, Schweiz.
Gynakol Geburtshilfliche Rundsch. 2005 Apr;45(2):107-15. doi: 10.1159/000083785.
To compare the rates of complications of dilatation and evacuation (D&E) in the second trimester of pregnancy.
Retrospective analysis of early complications after D&E in the second trimester (group A: 1988-1994) in comparison with D&E in the first trimester (group B: 1997) and with the induction of abortion by extra-amniotic application of prostaglandins in the second trimester of pregnancy (literature).
The overall complication rate of D&E was statistically significantly higher in the second than in the first trimester (p < 0.0001). The most frequent complication in both groups was a blood loss > 500 ml (p < 0.009). As with blood loss, there was a statistically significant increase in the incidence of postoperative bleeding (p < 0.001) and fever > 38 degrees C (p = 0.042) with rising gestational age, too. We registered similar rates for incomplete abortion, infection, cervical injury, uterine perforation and thrombosis.
Second-trimester pregnancy termination with D&E is associated with higher morbidity rates than in the first trimester. Overall, the rates of complications of D&E in our study were acceptable and comparable with the results of previous studies. Compared with the induction of abortion by extra-amniotic prostaglandins, D&E shows lower morbidity rates. In particular, the advantages of D&E are in the early second trimester.
比较妊娠中期扩张刮宫术(D&E)的并发症发生率。
回顾性分析妊娠中期D&E术后的早期并发症(A组:1988 - 1994年),并与妊娠早期的D&E(B组:1997年)以及妊娠中期经羊膜外应用前列腺素引产(文献报道)进行比较。
D&E的总体并发症发生率在妊娠中期显著高于妊娠早期(p < 0.0001)。两组最常见的并发症均为失血>500 ml(p < 0.009)。与失血情况相同,术后出血发生率(p < 0.001)和发热>38℃(p = 0.042)也随孕周增加而有统计学意义的升高。我们记录到的不全流产、感染、宫颈损伤、子宫穿孔和血栓形成的发生率相似。
妊娠中期采用D&E终止妊娠的发病率高于妊娠早期。总体而言,我们研究中D&E的并发症发生率是可接受的,且与以往研究结果相当。与经羊膜外前列腺素引产相比,D&E的发病率较低。特别是在妊娠中期早期,D&E具有优势。