Fenn N, Conn I G, German K A, Stephenson T P
Department of Urology, Royal Infirmary, Cardiff.
Br J Urol. 1992 Apr;69(4):366-8. doi: 10.1111/j.1464-410x.1992.tb15559.x.
A study was carried out on 112 patients who had undergone a clam procedure. Follow-up extended from 15 months to 8 years. The efficacy of the operation in achieving and maintaining continence in patients with instability and hyper-reflexia was confirmed (93% in the neuropathic group, 91% in the congenital instability group and 78% in the idiopathic group). Complications were common and included inability to void (requiring self-catheterisation), haematuria, mucus production and recurrent urinary tract infection. Complete bacteriological data were obtained on 80 patients; 30% were infected pre-operatively (all but 4 in the neuropathic group) but 66% had bacteriuria at the time of assessment after surgery. Subjectively, 17 patients (24%) who "never" got infected had bacteriuria, as did 29 (63%) of those who were "occasionally" infected. Objectively, 84% of patients on intermittent self-catheterisation (ISC) had positive cultures, but even in those voiding spontaneously bacteriuria was present in 60%. Careful follow-up of these patients is mandatory and a more rigorous approach to eradication of infection and subsequent prophylaxis has been instituted.
对112例接受了膀胱扩大术的患者进行了一项研究。随访时间从15个月延长至8年。证实了该手术在实现并维持不稳定和反射亢进患者控尿方面的疗效(神经病变组为93%,先天性不稳定组为91%,特发性组为78%)。并发症很常见,包括排尿困难(需要自我导尿)、血尿、黏液分泌和复发性尿路感染。获得了80例患者的完整细菌学数据;30%在术前感染(神经病变组除4例外全部感染),但术后评估时有66%存在菌尿。主观上,17例“从未”感染的患者有菌尿,“偶尔”感染的患者中有29例(63%)也有菌尿。客观上,84%接受间歇性自我导尿(ISC)的患者培养结果呈阳性,但即使是那些自主排尿的患者,菌尿发生率也为60%。对这些患者进行仔细随访是必不可少的,并且已经制定了更严格的感染根除及后续预防方法。