Sharfi A R, el Sir S, Beleil O
Department of Surgery, University of Khartoum, Sudan.
Br J Urol. 1992 Apr;69(4):369-71. doi: 10.1111/j.1464-410x.1992.tb15560.x.
A series of 52 patients with squamous cell carcinoma of the urinary bladder were studied over a 6-year period. They constituted 27% of all bladder tumours. The male:female ratio was 12:1; 62% of the patients were below the age of 50 years (mean 47) and 31% had a previous history of urinary bilharziasis. Associated stigmata of Schistosoma haematobium, as sandy patches, were detected in 69% of patients. Fourteen had bilharzial ureteric strictures as seen on intravenous urography and most of the tumours occurred in the region of the trigone; 60% had T3 NO MO tumours at presentation. Eighteen patients received radical radiotherapy and 16 patients under the age of 55 years underwent radical cystectomy with diversion of urine to an isolated rectum. The 5-year survival rate in the radical cystectomy group was 75%. Other modalities of treatment and their results are discussed.
在6年期间对52例膀胱鳞状细胞癌患者进行了研究。他们占所有膀胱肿瘤的27%。男女比例为12:1;62%的患者年龄在50岁以下(平均47岁),31%有泌尿生殖系血吸虫病病史。69%的患者检测到埃及血吸虫相关体征,如沙斑。静脉尿路造影显示14例有血吸虫性输尿管狭窄,大多数肿瘤发生在三角区;60%的患者初诊时为T3 NO MO肿瘤。18例患者接受了根治性放疗,16例55岁以下患者接受了根治性膀胱切除术并将尿液改道至孤立直肠。根治性膀胱切除术组的5年生存率为75%。还讨论了其他治疗方式及其结果。