Laslo Puskas, Slobodan Malobabić, Nela Puskas, Milos Malis, Rade Popović, Tatjana Ille
Department of Anatomy, Faculty of Medicine, Belgrade University, Belgrade, Serbia.
Int J Neurosci. 2005 May;115(5):669-79. doi: 10.1080/00207450590524340.
Interthalamic adhesion between the medial surfaces of the left and right thalamus is a variable structure and contains the midline thalamic nuclei, which are not much developed in humans. The research has been done on 6 human brains obtained during routine autopsy (age 45 to 65; 4 male and 2 female). Every tenth 10 microm thick frontal section was stained according to Klüver-Barrera method. In all cases the authors found a specific organization of certain groups of neurons within the interthalamic adhesion (IA) in form of circles on frontal sections. These circular groups were present on all sections but only 1-2 in each. The larger mean diameter of these circular arrangements was R = 229.4 microm, and smaller was r = 203.1 microm. These circular groups within the human IA were formed in average by 7.29 neurons. In periventricular region (PVR) of thalamus similar circular groups of neurons also were present in all cases as in IA. These neuronal groups in PVR were of smaller size than in the IA, with larger mean diameter R = 201.4, smaller mean diameter r = 181.2 microm and they contained fewer neurons, 6.69 on average. All three values (both diameters of circular arrangements, and number of neurons forming them) were significantly smaller in PVR (p < .01). Morphological types and sizes of neurons in both investigated structures (IA and PV) were not different. The circular neuronal groups in IA were formed in 61% of fusiform neurons and in PVR in 48% of fusiform neurons. According to their subependymal localization, size and form, these circular groups can represent in vivo correlates of neurospheres.
左右丘脑内侧表面之间的丘脑间粘合是一种可变结构，包含中线丘脑核，在人类中发育程度不高。研究选取了6例常规尸检获得的人脑（年龄45至65岁；4男2女）。每隔10个10微米厚的额叶切片按照克吕弗-巴雷拉法染色。在所有病例中，作者在额叶切片上发现丘脑间粘合（IA）内特定神经元群呈圆形的特定组织形式。这些圆形群组存在于所有切片上，但每个切片上只有1至2个。这些圆形排列的较大平均直径为R = 229.4微米，较小的为r = 203.1微米。人类IA内的这些圆形群组平均由7.29个神经元组成。在丘脑的室周区域（PVR），所有病例中也都存在与IA中类似的圆形神经元群组。PVR中的这些神经元群组比IA中的尺寸更小，较大平均直径R = 201.4，较小平均直径r = 181.2微米，且所含神经元更少，平均为6.69个。所有三个值（圆形排列的两个直径以及形成它们的神经元数量）在PVR中均显著更小（p < .01）。两个研究结构（IA和PV）中神经元的形态类型和大小并无差异。IA中的圆形神经元群组由61%的梭形神经元形成，PVR中由48%的梭形神经元形成。根据它们的室管膜下定位、大小和形态，这些圆形群组可能代表神经球的体内相关物。
