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大鼠下颌髁突中基质形成的(35S)-硫酸盐掺入研究。

Matrix formation in the mandibular condyle of the rat (35S) - sulfate incorporation studies.

作者信息

Katz M, Kvinnsland S

出版信息

Acta Odontol Scand. 1979;37(3):137-45. doi: 10.3109/00016357909004688.

DOI:10.3109/00016357909004688
PMID:158281
Abstract

The matrix formation activity of the mandibular condylar cartilage was investigated using radioactive sulfate incorporation. The condylar cartilage was studied at various developmental stages; as an autotransplant, in situ and on a chemically defined medium. An initial decrease in the cpm/DNA was followed by an increase, until a maximum was attained for all groups, between the 14th and 17th days. Thereafter, the matrix formation activity decreased. There was a surprising likeness in the patterns of activity for all the samples investigated. This tends to support the hypothesis that cartilagenous growth seem to be regulated, at least to some extent by one or more humoral factors.

摘要

采用放射性硫酸盐掺入法研究了下颌髁突软骨的基质形成活性。在不同发育阶段对髁突软骨进行了研究;作为自体移植,在原位以及在化学成分确定的培养基上进行研究。所有组的每分钟计数/DNA(cpm/DNA)最初均下降,随后上升,直至在第14天至第17天达到最大值。此后,基质形成活性下降。所有研究样本的活性模式都有惊人的相似之处。这倾向于支持这样一种假说,即软骨生长似乎至少在一定程度上受一种或多种体液因子的调节。

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引用本文的文献

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Perichondrial and endochondral components of mandibular condylar growth: morphometric and autoradiographic quantitation in rats.下颌髁突生长的软骨膜和软骨内成分:大鼠的形态计量学和放射自显影定量分析
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