Koyanagi Toshiya, Shimokawa T, Ida T, Kasegawa H, Tobaru T, Sumiyoshi T
Department of Cardiovascular Surgery, Sakakibara Heart Institute, Fuchu, Japan.
Kyobu Geka. 2005 Apr;58(4):262-6.
We treated 93 patients who developed left ventricular free wall rupture after acute myocardial infarction. Medical management including pericardial drainage was performed in 78 patients (84%), but 67 of them died. All 11 surviving patients showed an oozing type rupture. Surgical repair was performed in 15 patients (16%). As a result, 9 patients died and 6 survived. All but 1 of the patients who died presented with a blow-out rupture. Blow-out type rupture occurred in 3 and oozing type rupture in 3 of the surviving patients. One patient with blow-out type rupture underwent implantation of a left ventricular assist device following percutaneous cardiopulmonary support (PCPS), because of low output syndrome after the operation. The device was successfully removed 7 days after implantation. In all of the 3 patients with oozing type rupture, sutureless technique was successfully performed using fibrin-glue or fibrin-glue sheet fixation. After a mean follow-up period of 7 years after operation, 5 of 6 are still alive. To improve the clinical outcome of left ventricular free wall rupture, it is important for surgeons to closely liaise with physicians, to perform surgical repair as soon as possible, and to utilize a circulatory support system after operation. Therefore, we developed a new PCPS system compatible with emergency cardiac surgery and a new left ventricular assist system draining via the left ventricle.
我们对93例急性心肌梗死后发生左心室游离壁破裂的患者进行了治疗。78例患者(84%)接受了包括心包引流在内的内科治疗,但其中67例死亡。所有11例存活患者均表现为渗血型破裂。15例患者(16%)接受了手术修复。结果,9例患者死亡,6例存活。除1例死亡患者外,其余死亡患者均表现为破裂型破裂。存活患者中有3例发生破裂型破裂,3例发生渗血型破裂。1例破裂型破裂患者术后因低心排综合征在经皮心肺支持(PCPS)后植入了左心室辅助装置。该装置在植入7天后成功移除。在所有3例渗血型破裂患者中,均成功采用纤维蛋白胶或纤维蛋白胶片固定的无缝合技术。术后平均随访7年,6例患者中有5例仍存活。为改善左心室游离壁破裂的临床结局,外科医生与内科医生密切协作、尽早进行手术修复并在术后利用循环支持系统非常重要。因此,我们开发了一种与急诊心脏手术兼容的新型PCPS系统以及一种经左心室引流的新型左心室辅助系统。