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上颌骨和下颌骨的转移性视网膜母细胞瘤。

Metastatic retinoblastoma of the maxilla and mandible.

作者信息

Taguchi A, Suei Y, Ogawa I, Naito K, Nagasaki T, Lee K, Fujita M, Tanimoto K

机构信息

Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

出版信息

Dentomaxillofac Radiol. 2005 Mar;34(2):126-31. doi: 10.1259/dmfr/51279066.

Abstract

Metastatic retinoblastoma of the jaws is very rare. We present a 4-year-old boy with metastatic retinoblastoma that involved both the maxilla and mandible simultaneously. Enhanced CT indicated bone-destructive masses with partially non-enhanced area and enhanced margin in the right maxilla and left mandible. MRI showed well-delineated masses that were isointense on T(1) weighted images and hyperintense on T(2) weighted images. Four weeks after chemotherapy and bone marrow transplantation, the size of lesions remarkably decreased. The patient died 19 months later with extensive tumour metastases despite additional chemotherapy. In this case, the dental crypt of a permanent tooth was considered the potential target through which retinoblastoma metastasized to the jaws.

摘要

颌骨转移性视网膜母细胞瘤非常罕见。我们报告一例4岁男孩,患有同时累及上颌骨和下颌骨的转移性视网膜母细胞瘤。增强CT显示右侧上颌骨和左侧下颌骨有骨质破坏肿块,部分区域无强化,边缘强化。MRI显示肿块边界清晰,在T1加权像上呈等信号,在T2加权像上呈高信号。化疗和骨髓移植4周后,病变大小显著减小。尽管进行了额外化疗,患者在19个月后因广泛肿瘤转移而死亡。在该病例中,恒牙牙囊被认为是视网膜母细胞瘤转移至颌骨的潜在靶点。

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