Jagannath S, Barlogie B
Division of Hematology/Oncology, University of Arkansas for Medical Sciences, Little Rock.
Hematol Oncol Clin North Am. 1992 Apr;6(2):437-49.
Intensive cytotoxic chemotherapy is capable of more marked tumor cytoreduction including true complete remissions in multiple myeloma. Use of autologous marrow and blood stem cells as well as growth factors has reduced the risk of infection and severe extramedullary toxicities.
强化细胞毒性化疗能够更显著地减少肿瘤细胞数量,包括在多发性骨髓瘤中实现真正的完全缓解。使用自体骨髓和血液干细胞以及生长因子降低了感染风险和严重的髓外毒性。