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一些巴西金丝桃属植物的抗真菌活性。

Antifungal activity of some Brazilian Hypericum species.

作者信息

Fenner R, Sortino M, Rates S M Kuze, Dall'Agnol R, Ferraz A, Bernardi A P, Albring D, Nör C, von Poser G, Schapoval E, Zacchino S

机构信息

Programa de Pós Graduação em Ciências Farmacêuticas, UFRGS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Porto Alegre 90610-000, Brazil.

出版信息

Phytomedicine. 2005 Mar;12(3):236-40. doi: 10.1016/j.phymed.2003.11.004.

DOI:10.1016/j.phymed.2003.11.004
PMID:15830847
Abstract

Crude methanolic extracts and fractions from the aerial parts of seven species of Hypericum (H. caprifoliatum Cham. and Schltdl., H. carinatum Griseb., H. connatum Lam., H. ternum A. St.-Hil., H. myrianthum Cham. and Schltdl., H. piriai Arechav. and H. polyanthemum Klotzsch ex Reichardt) growing in southern Brazil were analyzed for their in vitro antifungal activity against a panel of standardized and clinical opportunistic pathogenic yeasts and filamentous fungi, including dermatophytes, by the agar dilution method. Chloroform and hexane extracts of H. ternum showed the greatest activity among extracts tested.

摘要

对生长在巴西南部的七种金丝桃属植物(金丝桃、龙骨金丝桃、合生金丝桃、三出金丝桃、多花金丝桃、皮氏金丝桃和多花金丝桃)地上部分的粗甲醇提取物和馏分进行分析,采用琼脂稀释法检测其对一组标准化和临床机会致病性酵母及丝状真菌(包括皮肤癣菌)的体外抗真菌活性。三出金丝桃的氯仿和己烷提取物在测试提取物中表现出最大活性。

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