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药物洗脱时代的被动支架涂层。

Passive stent coatings in the drug-eluting era.

作者信息

Menown Ian, Lowe Rob, Penn Ian

机构信息

Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, Canada.

出版信息

J Invasive Cardiol. 2005 Apr;17(4):222-8.

Abstract

Advances in coronary stent technology, both in terms of stent design and function, have significantly improved the safety and efficacy of percutaneous coronary intervention, including marked reduction in restenosis. This has led to its use in increasingly challenging clinical and lesional subsets, with potential for increased risk of stent-associated thrombosis. In this article we outline the development of passive stent coatings, and evaluate the ongoing role of such coatings in the contemporary era of antiproliferative drug-eluting stents.

摘要

冠状动脉支架技术在支架设计和功能方面的进展,显著提高了经皮冠状动脉介入治疗的安全性和有效性,包括再狭窄的明显减少。这使得其在越来越具有挑战性的临床和病变亚组中得到应用,同时增加了支架相关血栓形成的风险。在本文中,我们概述了被动支架涂层的发展,并评估了此类涂层在当代抗增殖药物洗脱支架时代的持续作用。

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