Howie Donald W, McGee Margaret A, Costi Kerry, Graves Stephen E
Department of Orthopaedics and Trauma, University of Adelaide and Royal Adelaide Hospital, L4 Bice Building, Adelaide, South Australia 5000, Australia.
Orthop Clin North Am. 2005 Apr;36(2):195-201, ix. doi: 10.1016/j.ocl.2004.12.001.
This article describes a randomized clinical trial in young patients, comparing metal-on-metal cemented resurfacing hip replacement with cemented total hip replacement. The trial was stopped early, mainly because of a high incidence of failure of the cemented resurfacing acetabular component. The results reinforce the importance of clinical trials for evaluating the safety and efficacy of prosthesis designs before being used in a large cohort of patients. Although there may be advantages of resurfacing hip replacement, trials are also required to demonstrate it has a midterm success that reasonably approaches that of total hip replacement.
本文描述了一项针对年轻患者的随机临床试验,比较金属对金属骨水泥型表面置换髋关节与骨水泥型全髋关节置换。该试验提前终止,主要原因是骨水泥型表面置换髋臼组件的失败发生率很高。这些结果强化了在将假体设计用于大量患者之前进行临床试验以评估其安全性和有效性的重要性。尽管表面置换髋关节可能有优势,但也需要通过试验来证明其中期成功率能合理接近全髋关节置换的成功率。