Zinkin Noah T, Peppercorn Mark A
Beth Israel Deaconess Medical Center, Harvard Medical school, 330 Brookline Ave., Rabb 4, Cambridge, MA 02215, USA.
Best Pract Res Clin Gastroenterol. 2005 Apr;19(2):263-74. doi: 10.1016/j.bpg.2004.10.001.
Abdominal epilepsy is an uncommon syndrome in which gastrointestinal complaints, most commonly abdominal pain, result from seizure activity. It is characterized by (1) otherwise unexplained, paroxysmal gastrointestinal complaints, (2) symptoms of a central nervous system disturbance, (3) an abnormal electroencephalogram with findings specific for a seizure disorder, and (4) improvement with anticonvulsant medication. We review the history of the syndrome and analyze all 36 cases reported in the English literature from the last 34 years. The most common gastrointestinal symptoms include abdominal pain, nausea and vomiting, while the most common neurological symptoms include lethargy and confusion. After exclusion of more common etiologies for the presenting complaints, workup should proceed with an electroencephalogram. Where the diagnosis is seriously considered, neurological consultation should be considered. Treatment typically begins with anticonvulsant medication, and resolution of symptoms with therapy helps to confirm the diagnosis.
腹型癫痫是一种罕见的综合征，其中胃肠道症状（最常见的是腹痛）由癫痫活动引起。其特征为：（1）无法用其他原因解释的阵发性胃肠道症状；（2）中枢神经系统紊乱症状；（3）脑电图异常且有癫痫障碍的特异性表现；（4）使用抗惊厥药物后症状改善。我们回顾了该综合征的历史，并分析了过去34年英文文献中报道的所有36例病例。最常见的胃肠道症状包括腹痛、恶心和呕吐，而最常见的神经症状包括嗜睡和意识模糊。在排除了导致现有症状的更常见病因后，应进行脑电图检查。当认真考虑诊断时，应考虑进行神经科会诊。治疗通常从抗惊厥药物开始，症状通过治疗得到缓解有助于确诊。
