Datta Jaydip, White Charles S, Gilkeson Robert C, Meyer Cristopher A, Kansal Sarita, Jani Manish L, Arildsen Ronald C, Read Katrina
Department of Radiology, Vanderbilt University, Nashville, Tenn, USA.
Radiology. 2005 Jun;235(3):812-8. doi: 10.1148/radiol.2353040314. Epub 2005 Apr 15.
To retrospectively determine the imaging features of anomalous coronary arteries depicted at multi-detector row computed tomographic (CT) angiography in 18 patients seen at four institutions.
Eighteen patients underwent imaging with a four- or 16-section multi-detector row CT unit by using retrospective electrocardiographic (ECG) gating after infusion of 120-150 mL of intravenous contrast material. Section thicknesses of 0.8-3.0 mm were achieved during breath holding, and images were reconstructed with a 50% overlap. Volumetric reconstructions were obtained for each patient. Each study was assessed retrospectively for the origin and course of the anomalous coronary artery by two thoracic radiologists; decisions were made in consensus. Institutional review board exemption and informed consent waiver was granted at each institution. The study was compliant with the Health Insurance Portability and Accountability Act.
Seventeen patients were referred because of equivocal findings at cardiac catheterization or echocardiography; in one, the anomalous coronary artery was incidental. A total of 20 anomalous vessels were found. Twelve patients with 14 variant vessels had an anomalous origin of a left coronary artery (right cusp, 13; noncoronary cusp, one). In four patients, an anomalous right coronary artery originated from the left side; one patient had a single coronary artery arising from the right cusp. In one patient, a left coronary artery-to-vein fistula was observed. In 10 patients, the anomalous vessel passed between the aorta and the main pulmonary artery or right ventricular outflow track. In each case, the origin of the anomalous coronary artery and its course in relationship to the great vessels were unequivocally demonstrated. Volumetric images were useful for showing the three-dimensional orientation of the anomalous coronary artery with respect to the great vessels and cardiac chambers.
Multi-detector row CT angiography provided accurate depiction of vessel origin and course in this review of 20 anomalous coronary arteries. The results of this study suggest that CT is a viable noninvasive modality for delineating coronary arterial anomalies, particularly if findings at coronary angiography are equivocal.
回顾性确定在四个机构就诊的18例患者中,多层螺旋计算机断层扫描(CT)血管造影所显示的异常冠状动脉的影像学特征。
18例患者在静脉注射120 - 150 mL造影剂后,采用回顾性心电图(ECG)门控技术,使用4排或16排多层螺旋CT设备进行成像。屏气期间层厚为0.8 - 3.0 mm,图像重建时重叠率为50%。为每位患者获取容积重建图像。两名胸部放射科医生对每项研究进行回顾性评估,以确定异常冠状动脉的起源和走行;达成一致意见后做出判断。各机构均获得了机构审查委员会的豁免和知情同意豁免。该研究符合《健康保险流通与责任法案》。
17例患者因心脏导管检查或超声心动图检查结果不明确而被转诊;1例患者的异常冠状动脉为偶然发现。共发现20条异常血管。12例患者有14条变异血管,其左冠状动脉起源异常(右冠瓣,13条;无冠瓣,1条)。4例患者的右冠状动脉起源于左侧;1例患者有一条起源于右冠瓣的单一冠状动脉。1例患者观察到左冠状动脉至静脉瘘。10例患者的异常血管走行于主动脉与主肺动脉或右心室流出道之间。在每种情况下,异常冠状动脉的起源及其与大血管的关系均得到明确显示。容积图像有助于显示异常冠状动脉相对于大血管和心腔的三维方向。
在对20条异常冠状动脉的回顾性研究中,多层螺旋CT血管造影能够准确显示血管的起源和走行。本研究结果表明,CT是一种可行的无创方法,用于描绘冠状动脉异常,特别是在冠状动脉造影结果不明确的情况下。