Schmid Michael, Achenbach Stephan, Ludwig Josef, Baum Ulrich, Anders Katharina, Pohle Karsten, Daniel Werner G, Ropers Dieter
Department of Internal Medicine II (Cardiology), University of Erlangen, Germany.
Int J Cardiol. 2006 Aug 28;111(3):430-5. doi: 10.1016/j.ijcard.2005.08.027. Epub 2005 Nov 4.
We investigated the potential of 16-slice multi-detector row spiral CT (MDCT) with retrospective ECG-gating for evaluation of coronary artery anomalies.
A total of 35 patients (23 men, 12 women, 19-81 years) in whom anomalous coronary arteries had been detected by invasive coronary angiography underwent MDCT (Sensation 16, Siemens, Germany). During one breathhold, a contrast-enhanced (90 ml, 5 ml/s) volume data set of the heart was acquired (16x0.75mm collimation, gantry rotation 375 ms). Images were reconstructed with a slice thickness of 1.0 mm in 0.5-mm intervals using retrospective ECG-gated reconstruction. The 35 data sets and 80 data sets of patients with angiographically normal coronary anatomy were analysed in random order concerning the origin and course of the coronary arteries. The results were compared to invasive coronary angiography.
All patients with coronary artery anomalies and all controls with normal coronary anatomy were identified by MDCT. In addition, the origins and course concerning their anatomical relationship to adjacent cardiac structures were visualized in all patients, including right-sided origin of the left main (n=10), left anterior descending coronary artery (n=4) or left circumflex coronary artery (n=10); left-sided origin of the right coronary artery (n=6); four coronary fistula to the pulmonary artery (two from the left anterior descending, one from the right coronary artery, one from the left main), and one fistula from the circumflex coronary artery to the left atrium
The study demonstrates that MDCT is a reliable noninvasive technique to identify and define anomalous coronary arteries and their course.
我们研究了16层多排螺旋CT(MDCT)结合回顾性心电图门控技术评估冠状动脉异常的潜力。
共有35例患者(23例男性,12例女性,年龄19 - 81岁),这些患者经有创冠状动脉造影检测出冠状动脉异常,接受了MDCT检查(德国西门子Sensation 16)。在一次屏气过程中,采集心脏的对比增强(90 ml,5 ml/s)容积数据集(准直16×0.75mm,机架旋转375 ms)。使用回顾性心电图门控重建技术,以1.0 mm的层厚、0.5 mm的间隔重建图像。对35例冠状动脉异常患者的数据集和80例冠状动脉造影显示正常的患者的数据集,随机分析冠状动脉的起源和走行。将结果与有创冠状动脉造影结果进行比较。
MDCT识别出了所有冠状动脉异常患者以及所有冠状动脉解剖结构正常的对照患者。此外,所有患者均清晰显示了冠状动脉起源和走行及其与相邻心脏结构的解剖关系,包括左主干(n = 10)、左前降支冠状动脉(n = 4)或左旋支冠状动脉(n = 10)起源于右侧;右冠状动脉起源于左侧(n = 6);4例冠状动脉瘘至肺动脉(2例来自左前降支,1例来自右冠状动脉,1例来自左主干),1例回旋支冠状动脉瘘至左心房。
该研究表明,MDCT是一种可靠的无创技术,可用于识别和明确冠状动脉异常及其走行。