Montero J A, Ruiz-Moreno J M
Instituto Oftalmológico de Alicante, Vitreo-Retinal Unit, Avenida de Denia 111, 03015 Alicante, Spain.
Br J Ophthalmol. 2005 May;89(5):562-4. doi: 10.1136/bjo.2004.049403.
To describe retinal findings in patients with idiopathic central serous chorioretinopathy (ICSC) as assessed by optical coherence tomography (OCT), and to compare them to fluorescein angiography (FA) findings.
Case series of 39 eyes from 36 patients with ICSC. Complete ophthalmological examination, last generation OCT (StratusOCT, Software version 3.1) and FA were performed. Six radial scans using OCT were performed and repeated. Singular findings were recorded, OCT images were measured and the results compared with those of FA. The main outcome measures were FA and OCT findings.
Two patterns of distinct OCT findings are described. In the first one, an optically empty vaulted area of different heights was observed under the neurosensory retina in 36 eyes, being related to fluorescein filled areas; in 35 of them, highly characteristic small bulges could be observed protruding from the retinal pigment epithelium (RPE), angiographically related to leaking spots. In the second pattern, three eyes showed an almost semicircular space under the RPE, with thinner overlying retina.
OCT may offer a new approach to the staging and knowledge of ICSC, and may help the understanding of the mechanisms of the disease.
描述经光学相干断层扫描(OCT)评估的特发性中心性浆液性脉络膜视网膜病变(ICSC)患者的视网膜表现,并将其与荧光素血管造影(FA)结果进行比较。
对36例ICSC患者的39只眼进行病例系列研究。进行了全面的眼科检查、最新一代OCT(StratusOCT,软件版本3.1)和FA检查。使用OCT进行6次径向扫描并重复。记录单个发现,测量OCT图像,并将结果与FA结果进行比较。主要观察指标为FA和OCT结果。
描述了两种不同的OCT表现模式。第一种模式下,在36只眼中,神经感觉视网膜下观察到不同高度的光学空的拱形区域,与荧光素填充区域相关;其中35只眼中,可观察到从视网膜色素上皮(RPE)突出的高度特征性小隆起,血管造影显示与渗漏点相关。第二种模式下,三只眼在RPE下显示出几乎半圆形的间隙,上方视网膜较薄。
OCT可能为ICSC的分期和认识提供一种新方法,并有助于理解该疾病的机制。