Hamdy A H, Kratzer D D, Paxton L M, Roberts B J
Avian Dis. 1979 Jan-Mar;23(1):164-73.
The efficacies of lincomycin (L) and spectinomycin (S), alone and in various combinations (L/S), were determined against Escherichia coli (EC) and Staphylococcus aureus (SA) of avian origin, both in vitro and in vivo. L contributed significantly to L/S activity against SA, while S contributed significantly to L/S activity against EC, and L/S (2.5 mg L + 5.0 mg S) was more effective than either L or S against SA and EC. The suggested optimum dose for controlling early chick mortality caused by SA and EC is 2.5/5.0 mg of L/S per chick.
分别测定了林可霉素(L)和壮观霉素(S)单独及以不同组合(L/S)形式对禽源大肠杆菌(EC)和金黄色葡萄球菌(SA)的体内外抗菌效果。L对L/S组合抗SA的活性有显著贡献,而S对L/S组合抗EC的活性有显著贡献,且L/S(2.5毫克L + 5.0毫克S)对SA和EC的抗菌效果比单独使用L或S更有效。建议控制由SA和EC引起的雏鸡早期死亡的最佳剂量为每只雏鸡2.5/5.0毫克的L/S。