Ma Jin, Wu De-zheng, Gao Ru-long, Lü Lin, Zhang Shao-chong, Li Chun-fang
Eye Center of Affiliated Second Hospital School of Medicine Zhejiang University, Hangzhou 310009, China.
Zhonghua Yan Ke Za Zhi. 2005 Mar;41(3):216-20.
To evaluate the conversion of macular function in diabetic macular edema (DME) after vitreous surgery.
Seventeen eyes of 16 patients were assessed after pars plana vitrectomy for DME. Multifocal electroretinogram (mfERG) techniques were used to evaluate the effects of treatment on macular visual function, and retinal foveal thickness was determined by optical coherence tomography before and after vitrectomy. Patients were followed up continually for 7 months. The correlation between the change of tomographic features and visual functions were analyzed.
During the follow-up period, the retinal function in macular areas recovered and the foveal thickness decreased gradually. While compared with preoperative values, the response of positive wave (P1) have shown decreases in implicit time and increases in amplitude since the forth and fifth postoperative month respectively (P < 0.05). While compared between each postoperative period, the P1 responses have increased significantly since the forth postoperative month. The correlation between the increase of P1 amplitude in macular area and the decrease of retinal foveal thickness was significant (r = 0.954, P < 0.001).
Macular function get improvement gradually in DME after vitreous surgery; The restoration of macular function is coincident with the reduction of macular edema.
评估玻璃体手术后糖尿病性黄斑水肿(DME)患者黄斑功能的转变情况。
对16例患者的17只眼睛行DME的玻璃体切除术后进行评估。采用多焦视网膜电图(mfERG)技术评估治疗对黄斑视觉功能的影响,并在玻璃体切除术前和术后通过光学相干断层扫描测定视网膜中央凹厚度。对患者进行连续7个月的随访。分析断层扫描特征变化与视觉功能之间的相关性。
在随访期间,黄斑区视网膜功能恢复,中央凹厚度逐渐降低。与术前值相比,自术后第4个月和第5个月起,正向波(P1)反应的潜伏时间分别缩短,波幅分别增加(P<0.05)。在各术后时期之间比较,自术后第4个月起P1反应显著增加。黄斑区P1波幅增加与视网膜中央凹厚度降低之间的相关性显著(r=0.954,P<0.001)。
玻璃体手术后DME患者的黄斑功能逐渐改善;黄斑功能的恢复与黄斑水肿的减轻相一致。