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糖尿病性黄斑水肿患者行玻璃体切割术后白内障超声乳化术后黄斑厚度的变化。

Macular thickness changes after phacoemulsification in previously vitrectomized eyes for diabetic macular edema.

机构信息

Department of Ophthalmology, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey.

出版信息

Retina. 2011 Jun;31(6):1095-100. doi: 10.1097/IAE.0b013e3181f98cd5.

DOI:10.1097/IAE.0b013e3181f98cd5
PMID:21293315
Abstract

PURPOSE

To report visual results and anatomical outcome after uncomplicated phacoemulsification in eyes that previously underwent pars plana vitrectomy for diabetic macular edema.

METHODS

This retrospective noncomparative study included 22 eyes of 19 diabetic patients who underwent uncomplicated cataract surgery with phacoemulsification and intraocular lens implantation after pars plana vitrectomy with internal limiting membrane removal for diabetic macular edema. Main outcome measures included visual acuity and foveal thickness (FT) changes as assessed by optical coherence tomography. Wilcoxon test was used for statistical analysis.

RESULTS

Mean follow-up time was 11.9 ± 8.75 months. Mean FT increased by 20.5 ± 67.6 μm (8.4%), with a mean preoperative FT of 237 ± 69 μm compared with a mean postoperative FT of 257.6 ± 89.8 μm (P = 0.236). Foveal thickness increased by at least 20% in 6 eyes (27.3%), remained within 20% in 14 eyes (63.6%), and decreased by 20% in 2 eyes (9.1%). Visual acuity improved by ≥2 lines in 16 eyes (72.7%) and remained stable in 6 eyes (27.3%). Visual acuity was 20/40 or better in 11 eyes (50%).

CONCLUSION

Moderate but insignificant increase in FT was observed after phacoemulsification in eyes that previously underwent pars plana vitrectomy for diabetic macular edema. Prospective studies with a large number of patients are warranted for a more reliable conclusion.

摘要

目的

报告在先前因糖尿病性黄斑水肿行标准经睫状体平坦部玻璃体切除术(PPV)联合内界膜剥除术后行超声乳化白内障吸除术(Phaco)的眼中,无并发症的 Phaco 术后的视力结果和解剖结果。

方法

本回顾性非对照研究纳入了 19 例糖尿病患者的 22 只眼,这些患者先前因糖尿病性黄斑水肿行标准经睫状体平坦部玻璃体切除术联合内界膜剥除术,之后行超声乳化白内障吸除术并植入人工晶状体。主要观察指标包括视力和黄斑中心凹厚度(FT)的变化,通过光学相干断层扫描(OCT)评估。采用 Wilcoxon 检验进行统计学分析。

结果

平均随访时间为 11.9±8.75 个月。平均 FT 增加 20.5±67.6μm(8.4%),术前 FT 平均值为 237±69μm,术后 FT 平均值为 257.6±89.8μm(P=0.236)。6 只眼(27.3%)的 FT 增加至少 20%,14 只眼(63.6%)的 FT 增加在 20%以内,2 只眼(9.1%)的 FT 减少 20%。16 只眼(72.7%)的视力提高至少 2 行,6 只眼(27.3%)的视力保持稳定。11 只眼(50%)的视力达到 20/40 或更好。

结论

在先前因糖尿病性黄斑水肿行标准经睫状体平坦部玻璃体切除术联合内界膜剥除术的眼中,行 Phaco 后 FT 适度但无统计学意义的增加。需要进行前瞻性、大样本量的研究,以得出更可靠的结论。

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