Pollock F E, Smith T L, Koman L A
Department of Physiology and Pharmacology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157.
Microvasc Res. 1992 Mar;43(2):227-34. doi: 10.1016/0026-2862(92)90019-l.
A new implantable window was developed in order to study the native microcirculation of the rabbit ear. The responses of the ear microvasculature to total body cooling were studied before and after implantation of the window. No differences were found between arteriolar and venular vasoconstriction with cooling before and after implantation of the window. Arteriolar constriction was significantly greater than the venular response both before and after placement of the window (P = 0.014). Surface skin temperature of the instrumented and control ears was similar at room temperature (35.2 +/- 2.6 versus 36.1 +/- 1.0 degrees, respectively; P = 0.280); however, the instrumented ear was slightly warmer during cooling (17.9 +/- 1.9 versus 15.2 +/- 3.1 degrees; P = 0.024), suggesting increased blood flow in the instrumented ear. Details of construction and implantation of the window are described.
为了研究兔耳的天然微循环，开发了一种新型可植入窗口。在植入窗口前后，研究了耳部微血管系统对全身冷却的反应。在植入窗口前后，冷却时小动脉和小静脉的血管收缩没有差异。在放置窗口前后，小动脉收缩均显著大于小静脉反应（P = 0.014）。在室温下，装有仪器的耳朵和对照耳朵的表面皮肤温度相似（分别为35.2±2.6摄氏度和36.1±1.0摄氏度；P = 0.280）；然而，在冷却过程中，装有仪器的耳朵略暖和一些（17.9±1.9摄氏度和15.2±3.1摄氏度；P = 0.024），这表明装有仪器的耳朵血流量增加。文中描述了窗口的构造和植入细节。
