Kenny D
Blood Center of Southeastern Wisconsin, Milwaukee 53233-2194.
Med Hypotheses. 1992 Feb;37(2):97-9. doi: 10.1016/0306-9877(92)90047-g.
Dietary fish oil supplementation has received considerable interest as a non-pharmacological adjuvant in the treatment of several diseases, especially hypertension. However, epidemiological, clinical, and experimental evidence conflict. A hypothesis is proposed that fish oil, may have a variable effect on vascular reactivity and consequently, blood pressure. A mechanism is proposed and reasons for the variation in the literature suggested. On the basis of this analysis a potentially adverse effect of dietary fish oil on blood pressure in some individuals is suggested.
作为治疗多种疾病尤其是高血压的一种非药物辅助手段,膳食补充鱼油已引起了广泛关注。然而,流行病学、临床及实验证据却相互矛盾。本文提出一个假说,即鱼油可能对血管反应性进而对血压产生不同的影响。文中提出了一种机制,并说明了文献中出现这种差异的原因。基于这一分析,提示了膳食鱼油对某些个体血压可能产生的不良影响。