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主动脉缩窄扩大弓修复术后的结果。

Outcome after extended arch repair for aortic coarctation.

作者信息

Thomson J D R, Mulpur A, Guerrero R, Nagy Z, Gibbs J L, Watterson K G

机构信息

Department of Congenital Cardiology, Yorkshire Heart Centre, Leeds General Infirmary, Leeds, UK.

出版信息

Heart. 2006 Jan;92(1):90-4. doi: 10.1136/hrt.2004.058685. Epub 2005 Apr 21.

Abstract

OBJECTIVES

To assess survival and long term arch patency rates in a consecutive group of children after extended arch repair for coarctation of the aorta.

METHODS

Review of 191 consecutive children (154 (81%) under 1 year of age) operated on between 1990 and 2002 by a single surgeon using extended arch reconstructive techniques. For assessment of survival patients were divided into three groups: 1, coarctation alone, n = 104; 2, coarctation and ventricular septal defect, n = 38; and 3, coarctation in association with complex intracardiac anomalies, n = 49. A prospective and systematic clinical and echocardiographic evaluation of the aortic arch was undertaken.

RESULTS

Median time to follow up was 4.2 years (range 1-10.6 years). Overall actuarial survival was 92%, 88%, and 88% at two, five, and 10 years. Mortality was significantly higher in those patients with complex intracardiac anatomy. Arch obstruction recurred in seven of 165 (4.2%) patients: four of 139 (2.9%) term and three of 10 (30%) premature infants (p < 0.001).

CONCLUSIONS

Survival after extended arch reconstruction for coarctation is excellent. At long follow up recurrent arch obstruction is rare, with prematurity the only risk factor.

摘要

目的

评估一组连续接受主动脉缩窄扩大主动脉弓修复术的儿童的生存率和主动脉弓长期通畅率。

方法

回顾1990年至2002年间由单一外科医生采用扩大主动脉弓重建技术手术治疗的191例连续儿童(154例(81%)年龄小于1岁)。为评估生存率,将患者分为三组:1. 单纯主动脉缩窄,n = 104;2. 主动脉缩窄合并室间隔缺损,n = 38;3. 主动脉缩窄合并复杂心内畸形,n = 49。对主动脉弓进行前瞻性、系统性的临床和超声心动图评估。

结果

中位随访时间为4.2年(范围1 - 10.6年)。2年、5年和10年的总体精算生存率分别为92%、88%和88%。复杂心内解剖结构的患者死亡率显著更高。165例患者中有7例(4.2%)出现主动脉弓梗阻复发:足月儿139例中有4例(2.9%),早产儿10例中有3例(30%)(p < 0.001)。

结论

主动脉缩窄扩大主动脉弓重建术后生存率良好。长期随访中,主动脉弓梗阻复发罕见,早产是唯一的风险因素。

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