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囊内白内障摘除术后痤疮丙酸杆菌性眼内炎

Propionibacterium acnes endophthalmitis after intracapsular cataract extraction.

作者信息

Chien A M, Raber I M, Fischer D H, Eagle R C, Naidoff M A

机构信息

Cornea Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107.

出版信息

Ophthalmology. 1992 Apr;99(4):487-90. doi: 10.1016/s0161-6420(92)31923-2.

DOI:10.1016/s0161-6420(92)31923-2
PMID:1584564
Abstract

The authors report a case of Propionibacterium acnes endophthalmitis after intracapsular cataract extraction with implantation of an anterior chamber intraocular lens. The patient's chronic inflammation persisted for 5 years after cataract surgery despite treatment with pars plana vitrectomy, intraocular lens removal, topical and oral steroids, and topical fortified antibiotics. Fluctuations in the inflammation were paralleled by changes in the size and appearance of a white plaque on the posterior corneal surface. Anterior chamber tap cultures were positive for P. acnes after 8 days of incubation under anaerobic conditions. The inflammation was not controlled until the posterior corneal plaque, which was the presumed nidus of the chronic infection, was removed and the patient was treated with intravitreal and oral antibiotics.

摘要

作者报告了1例在囊内白内障摘除并植入前房型人工晶状体后发生痤疮丙酸杆菌性眼内炎的病例。尽管接受了玻璃体切割术、人工晶状体取出术、局部和口服类固醇以及局部强化抗生素治疗,但患者白内障手术后的慢性炎症仍持续了5年。炎症的波动与后角膜表面白色斑块的大小和外观变化同步。在前房穿刺液在厌氧条件下培养8天后,痤疮丙酸杆菌培养呈阳性。直到移除被认为是慢性感染病灶的后角膜斑块并对患者进行玻璃体内和口服抗生素治疗后,炎症才得到控制。

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引用本文的文献

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Chronic postoperative endophthalmitis: a review of clinical characteristics, microbiology, treatment strategies, and outcomes.慢性术后眼内炎:临床特征、微生物学、治疗策略及预后的综述
Int J Inflam. 2012;2012:313248. doi: 10.1155/2012/313248. Epub 2012 Feb 22.
2
Uveitis in the elderly--is it easy to identify the masquerade?老年葡萄膜炎——伪装综合征容易识别吗?
Br J Ophthalmol. 1997 Oct;81(10):827-31. doi: 10.1136/bjo.81.10.827.
3
Corynebacterium minutissimum endophthalmitis: management with antibiotic irrigation of the capsular bag.
极小棒状杆菌性眼内炎:采用抗生素冲洗囊袋的治疗方法
Int Ophthalmol. 1995;19(5):313-6. doi: 10.1007/BF00130928.
4
Aggressive management of an epidemic of chronic pseudophakic endophthalmitis: results and literature survey.慢性人工晶状体眼内炎流行的积极管理:结果与文献综述
Br J Ophthalmol. 1994 Feb;78(2):115-9. doi: 10.1136/bjo.78.2.115.
5
Antibiotic prophylaxis in corneal storage media.角膜保存介质中的抗生素预防
Trans Am Ophthalmol Soc. 1994;92:181-96; discussion 196-201.