Kostera-Pruszczyk Anna, Emeryk-Szajewska Barbara
Klinika Neurologii AM w Warszawie.
Ginekol Pol. 2005 Feb;76(2):122-6.
We retrospectively analyzed the course and outcome of pregnancy in a group of 26 women with myasthenia gravis. Premature births were noted in 7.9% of pregnancies, the rate of cesarean section was 15.8%. Neonatal myasthenia was observed in 10 children born by 5 women (16% of the mothers). There were three neonatal deaths: two due to neonatal myasthenia, one in a child born with multiple congenital anomalies. Transient exacerbation of MG symptoms was observed during four pregnancies (10.5%). MG is not associated with increased risk for MG patient and the newborn. Giving birth to one child with transient MG increases the risk of transient MG in consecutive pregnancies.
我们回顾性分析了一组26例重症肌无力女性患者的妊娠过程及结局。7.9%的妊娠出现早产,剖宫产率为15.8%。5名女性所生的10名婴儿(占母亲的16%)出现新生儿重症肌无力。有3例新生儿死亡:2例死于新生儿重症肌无力,1例死于伴有多种先天性畸形的患儿。4例妊娠(10.5%)期间观察到重症肌无力症状短暂加重。重症肌无力与重症肌无力患者及其新生儿的风险增加无关。生育一名患有短暂性重症肌无力的患儿会增加后续妊娠中出现短暂性重症肌无力的风险。