Harms J, Bartels M, Bourquain H, Peitgen H O, Schulz T, Kahn T, Hauss J, Fangmann J
Department of Visceral-, Transplantation-, Vascular- and Thoracic Surgery, University of Leipzig, Leipzig, Germany.
Transplant Proc. 2005 Mar;37(2):1059-62. doi: 10.1016/j.transproceed.2004.11.088.
For living donor liver transplantation (LDLT) accurate diagnostic workup is essential. Multiple imaging approaches are currently used. Problems arise in the assessment of vascular and bile duct anatomy, liver graft volume, and vascular territories involved. A 3D visualization system that improves anatomic assessment, allows interactive surgery planning, and acts as an intraoperative guide with enhanced precision is required. Refinements in computed tomography (CT) technology with the introduction of multidetector-row CT scanners and implementation of mathematical methods on computerized digital data has enabled CT-based 3D visualizations.
Sixteen LDLT candidates and three LDLT recipients were assessed by multislice CT examination. Image processing of the digital raw data for 3D visualization included segmentation and calculation of center lines. A hierarchical mathematical model representing the vascular and biliary tree was created. This allowed calculation of individual vascular territories.
3D CT-based visualization in LDLT facilitates diagnostic workup with high accuracy for analyses of vascular and bile duct variants, volumetry, and assessment of the optimal surgical splitting line of the living donor liver. Resultant areas of either arterial devascularization or venous congestion can be displayed and quantified preoperatively. The diagnostic method is of major impact on patient selection and directly influences intraoperative surgical guidance. The currently practiced "multiple imaging approach" approach, especially with regard to invasive diagnostics, can be avoided in the future.
对于活体肝移植(LDLT)而言,准确的诊断检查至关重要。目前采用多种成像方法。在评估血管和胆管解剖结构、肝移植体积以及涉及的血管区域时会出现问题。需要一种三维可视化系统,该系统能改善解剖评估、允许交互式手术规划并作为具有更高精度的术中指导。随着多层螺旋CT扫描仪的引入以及在计算机数字数据上实施数学方法,计算机断层扫描(CT)技术的改进使得基于CT的三维可视化成为可能。
对16例活体肝移植候选者和3例活体肝移植受者进行了多层CT检查评估。用于三维可视化的数字原始数据的图像处理包括分割和中心线计算。创建了一个表示血管和胆管树的分层数学模型。这使得能够计算个体血管区域。
基于三维CT的可视化在活体肝移植中有助于进行诊断检查,对于分析血管和胆管变异、体积测量以及评估活体供肝的最佳手术分割线具有高精度。术前可以显示并量化动脉血运障碍或静脉淤血的结果区域。该诊断方法对患者选择有重大影响,并直接影响术中手术指导。未来可以避免目前采用的“多种成像方法”,尤其是在侵入性诊断方面。