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植入机械辅助装置后行心脏移植引发的创伤后应激障碍:患者及其伴侣的评估

Posttraumatic stress disorder after implantation of a mechanical assist device followed by heart transplantation: evaluation of patients and partners.

作者信息

Bunzel B, Laederach-Hofmann K, Wieselthaler G M, Roethy W, Drees G

机构信息

Department of Cardiothoracic Surgery, Medical University Vienna, Wien, Austria.

出版信息

Transplant Proc. 2005 Mar;37(2):1365-8. doi: 10.1016/j.transproceed.2004.12.248.

DOI:10.1016/j.transproceed.2004.12.248
PMID:15848722
Abstract

AIM

We sought to investigate the prevalence of posttraumatic stress disorder, anxiety, and depression in patients and their partners after implantation of a mechanical assist device as a bridge to heart transplantation.

METHODS

This was a retrospective assessment of 41 patients (age 46.3 +/- 12.0 years; male-female ratio, 38:3; time since transplantation, 55.3 +/- 34.2 months [range, 7-122 months) and 27 partners (male-female ratio 2:25) by standardized instruments (Impact of Event Scale, Hospital Anxiety and Depression Scale), in 2 University Heart Transplant Centers (Vienna, Austria, Munster, Germany). The duration of the support systems (MicroMed DeBakey-VAD in 17 patients, Novacor in 10, Thoratec in 8, TCI HeartMate in 5, and Berlin Heart Incor in 1 patient) ranged from 28 to 711 (176 +/- 146) days.

RESULTS

None of the patients, but 23% of the partners (n = 6), met the criteria for posttraumatic stress disorder (Maercker cutoff >0). The Impact of Event Scale (IES) sum scales differed significantly between the 2 groups (21.2 +/- 15.1, mean +/- SD) for the patients versus 38.1 +/- 27.8 for the partners, respectively; P = .001). Two percent of the patients, but 19% of the partners, showed mild to moderate depression; 4% of patients, but 23% of their partners, reported mild to moderate anxiety. None of the results were significantly influenced by the time since transplantation, patient age, diagnoses, type of assist device, or indication for heart transplantation.

CONCLUSIONS

Despite patients being much closer to a life threat, their partners experience significantly more psychologic distress even in the long run. Our findings highlight the need for attention to the supporting persons.

摘要

目的

我们试图调查作为心脏移植桥梁的机械辅助装置植入后患者及其伴侣中创伤后应激障碍、焦虑和抑郁的患病率。

方法

这是一项在2个大学心脏移植中心(奥地利维也纳、德国明斯特)对41例患者(年龄46.3±12.0岁;男女比例38:3;移植后时间55.3±34.2个月[范围7 - 122个月])和27名伴侣(男女比例2:25)进行的回顾性评估,采用标准化工具(事件影响量表、医院焦虑抑郁量表)。支持系统的使用时长(17例患者使用MicroMed DeBakey - VAD,10例使用Novacor,8例使用Thoratec,5例使用TCI HeartMate,1例使用柏林心脏Incor)为28至711(176±146)天。

结果

患者中无人符合创伤后应激障碍标准(Maercker临界值>0),但23%的伴侣(n = 6)符合该标准。事件影响量表(IES)总分在两组间差异显著,患者组为21.2±15.1(均值±标准差),伴侣组为38.1±27.8;P = 0.001)。2%的患者有轻度至中度抑郁,但其伴侣中有19%;4%的患者报告有轻度至中度焦虑,但其伴侣中有23%。移植后时间、患者年龄、诊断、辅助装置类型或心脏移植指征均未对结果产生显著影响。

结论

尽管患者更接近生命威胁,但即使从长远来看,他们的伴侣经历的心理困扰明显更多。我们的研究结果凸显了关注支持人员的必要性。

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