心理症状与心室辅助装置植入的关系。
The Relationship Between Psychological Symptoms and Ventricular Assist Device Implantation.
机构信息
Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
出版信息
J Pain Symptom Manage. 2017 Dec;54(6):870-876.e1. doi: 10.1016/j.jpainsymman.2017.05.002. Epub 2017 Aug 12.
CONTEXT
Ventricular assist devices (VADs) improve quality of life in advanced heart failure patients, but there are little data exploring psychological symptoms in this population.
OBJECTIVE
This study examined the prevalence of psychiatric symptoms and disease over time in VAD patients.
METHODS
This prospective multicenter cohort study enrolled patients immediately before or after VAD implant and followed them up to 48 weeks. Depression and anxiety were assessed with Patient-Reported Outcomes Measurement Information System Short Form 8a questionnaires. The panic disorder, acute stress disorder (ASD) and post-traumatic stress disorder (PTSD) modules of the Structured Clinical Interview for the DSM were used.
RESULTS
Eighty-seven patients were enrolled. After implant, depression and anxiety scores decreased significantly over time (P = 0.03 and P < 0.001, respectively). Two patients met criteria for panic disorder early after implantation, but symptoms resolved over time. None met criteria for ASD or PTSD.
CONCLUSIONS
Our study suggests VADs do not cause serious psychological harms and may have a positive impact on depression and anxiety. Furthermore, VADs did not induce PTSD, panic disorder, or ASD in this cohort.
背景
心室辅助装置（VAD）可改善晚期心力衰竭患者的生活质量，但有关该人群心理症状的数据较少。
目的
本研究探讨了 VAD 患者随时间推移的精神症状和疾病的发生率。
方法
这项前瞻性多中心队列研究纳入了 VAD 植入前或植入后的患者，并对其进行了 48 周的随访。使用患者报告的结局测量信息系统简表 8a 问卷评估抑郁和焦虑。采用 DSM 的结构化临床访谈对惊恐障碍、急性应激障碍（ASD）和创伤后应激障碍（PTSD）模块进行评估。
结果
共纳入 87 例患者。植入后，抑郁和焦虑评分随时间显著降低（P=0.03 和 P<0.001）。2 例患者在植入后早期符合惊恐障碍标准，但症状随时间缓解。无一例符合 ASD 或 PTSD 标准。
结论
我们的研究表明，VAD 不会造成严重的心理伤害，并且可能对抑郁和焦虑有积极影响。此外，在本队列中，VAD 未引起 PTSD、惊恐障碍或 ASD。
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