Woods Margo N
Nutrition/Infection Unit, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Nutr Clin Care. 2005 Jan-Mar;8(1):24-30.
Hypertriglyceridemia and insulin resistance have been seen in patients with HIV. Beneficial effects of the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been reported for these conditions. One study of n-3 fatty acid supplementation in patients with HIV reported a decrease in serum triglyceride levels. These marine fatty acids appear to be working at a number of sites to achieve an improvement in lipid metabolism and insulin sensitivity. There is disagreement about the amount of n-3 fatty acids needed to achieve different effects and about the optimal ratio of dietary n-6 and n-3 fatty acids.
HIV患者中已出现高甘油三酯血症和胰岛素抵抗。据报道，n-3脂肪酸二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）对这些病症有有益作用。一项关于HIV患者补充n-3脂肪酸的研究报告称血清甘油三酯水平有所降低。这些海洋脂肪酸似乎在多个部位发挥作用，以改善脂质代谢和胰岛素敏感性。对于实现不同效果所需的n-3脂肪酸量以及饮食中n-6和n-3脂肪酸的最佳比例存在分歧。
