Zanardi M, Bonamini M, Rossi M
Divisione neurologica, USL 11, Ospedale, Genova Sampierdarena.
Recenti Prog Med. 1992 Mar;83(3):136-9.
The Authors present a case of type I Arnold-Chiari malformation (ACM), with early appearance of clinical symptoms and worsening course of the illness even after surgical treatment. The interest of the case rest both in the rich symptomatology and multiple exams performed which represent the evolution of the neuroradiological techniques of the last thirty years for the study of ACM. Recently, neurophysiologic exams such as somatosensory evoked potentials (SEP) helped to further evaluate these patients. Despite such diagnostic evolution, there is no definite etiopathogenesis. Furthermore, as for therapeutics, the best approach is still the Gardner surgical technique, which, at the moment, is debated for frequent post-operative complications and the absence of significant clinical improvement, especially in the most severe cases.
作者介绍了一例I型阿诺德-奇亚里畸形（ACM）病例，临床症状出现早，即使经过手术治疗病情仍呈恶化趋势。该病例的意义在于其丰富的症状表现以及进行的多项检查，这些检查代表了过去三十年用于研究ACM的神经放射学技术的发展。最近，诸如体感诱发电位（SEP）等神经生理学检查有助于进一步评估这些患者。尽管诊断技术有了这样的发展，但仍没有明确的病因。此外，在治疗方面，最佳方法仍然是加德纳手术技术，目前该技术因术后并发症频发且缺乏显著的临床改善效果而备受争议，尤其是在最严重的病例中。
