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[关于舒张性心力衰竭的当前知识]

[Current knowledge on diastolic heart failure].

作者信息

Misztal Marcin, Gackowski Andrzej, Piwowarska Wiesława

机构信息

Klinika Choroby Wieńcowej, Instytutu Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Lek. 2004;61(12):1428-32.

PMID:15850342
Abstract

Heart failure (HF) is still one of the most common causes of hospitalisation. Originally it was understood as systolic function impairment, but it is prooved that 40 to 50 percent of patients with clinical symptoms of HF have normal systolic function. These data lead to diagnosis of diastolic heart failure (DHF). The diastoly of the left ventricle consists of four stages: isovolumetric relaxation, early mitral inflow, slow mitral inflow and left atrium contraction. Authors have presented definition, epidemiology and basic pathophysiology of DHF. The categories of myocardial and non-myocardial pathogenic mechanisms have also been described. The clinical symptoms that allow to distinguish diastolic from systolic heart failure (SHF) have been pointed. The most common disorders that affect diastolic function like hypertension, coronary artery disease and diabetes have been described. Recent guidelines on therapy in diastolic heart failure have been also presented.

摘要

心力衰竭(HF)仍然是住院治疗的最常见原因之一。最初,它被理解为收缩功能受损,但事实证明,40%至50%有心力衰竭临床症状的患者收缩功能正常。这些数据促使了舒张性心力衰竭(DHF)的诊断。左心室舒张包括四个阶段:等容舒张期、二尖瓣早期血流充盈、二尖瓣血流缓慢充盈和左心房收缩。作者介绍了舒张性心力衰竭的定义、流行病学和基本病理生理学。还描述了心肌和非心肌致病机制的类别。指出了有助于区分舒张性心力衰竭与收缩性心力衰竭(SHF)的临床症状。描述了影响舒张功能的最常见疾病,如高血压、冠状动脉疾病和糖尿病。还介绍了舒张性心力衰竭的最新治疗指南。

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