Findling James W, Raff Hershel
Endocrine-Diabetes Center, St. Luke's Medical Center, 2801 West KK River Parkway, Suite 245, Milwaukee, WI 53215, USA.
Endocrinol Metab Clin North Am. 2005 Jun;34(2):385-402, ix-x. doi: 10.1016/j.ecl.2005.02.001.
Screening studies in high-risk populations have suggested that Cushing's syndrome is more common than previously appreciated. Patients who have specific signs and symptoms or clinical diagnoses known to be associated with hypercortisolism should be considered for screening. The measurement of late-night salivary cortisol provides the most sensitive method for screening, and urine-free cortisol and low-dose dexamethasone suppression testing may be used for confirmation of the diagnosis of endogenous hypercortisolism
针对高危人群的筛查研究表明，库欣综合征比之前认为的更为常见。有特定体征、症状或已知与皮质醇增多症相关的临床诊断的患者应考虑进行筛查。测定午夜唾液皮质醇是最敏感的筛查方法，尿游离皮质醇和小剂量地塞米松抑制试验可用于确诊内源性皮质醇增多症。
