Tanner Hildegard, Lukac Peter, Schwick Nicola, Fuhrer Juerg, Pedersen Anders Kirstein, Hansen Peter Steen, Delacretaz Etienne
Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland.
Heart Rhythm. 2004 Sep;1(3):268-75. doi: 10.1016/j.hrthm.2004.04.020.
The aim of this study was to evaluate irrigated-tip catheter for ablation of intraatrial reentrant tachycardias late after surgical repair of congenital heart disease.
In congenital heart disease patients, the right atrium can be markedly enlarged with areas of low blood flow. Radiofrequency (RF) lesion creation may be hampered by insufficient electrode cooling at sites with low blood flow.
Thirty-six consecutive patients with intraatrial reentrant tachycardia refractory to antiarrhythmic therapy from two centers were included in the study. Entrainment pacing and electroanatomic mapping (CARTO) were used to delineate reentrant circuits and critical isthmus sites. RF ablation was performed using an irrigated-tip catheter (Navistar Thermocool).
Fifty-two intraatrial reentrant tachycardia circuits were identified, and 48 were targeted with RF ablation. RF ablation was performed using a mean of 13 +/- 11 irrigated RF applications per tachycardia isthmus with a mean power of 36 +/- 8 W. In a historical control group of congenital heart disease patients managed with conventional catheter ablation, the number of lesions per isthmus was higher (23 +/- 11) and mean power was lower (27 +/- 14 W). Acute success was achieved in 45 intraatrial reentrant tachycardias (94% of targeted tachycardias and 87% of all tachycardias). After a mean follow-up of 17 +/- 7 months, 33 (92%) of 36 patients were free of recurrence. Five patients (14%) developed paroxysmal atrial fibrillation.
The combination of modern techniques including electroanatomic mapping and catheter irrigation allows safe and highly effective ablation of intraatrial reentrant tachycardia in patients with surgically repaired congenital heart disease.
本研究旨在评估灌注式尖端导管用于先天性心脏病手术修复术后晚期房内折返性心动过速的消融效果。
在先天性心脏病患者中,右心房可能会显著扩大且存在低血流区域。在低血流部位,电极冷却不足可能会妨碍射频(RF)损伤灶的形成。
本研究纳入了来自两个中心的36例对抗心律失常治疗无效的房内折返性心动过速患者。采用拖带起搏和电解剖标测(CARTO)来描绘折返环路和关键峡部位置。使用灌注式尖端导管(Navistar Thermocool)进行射频消融。
共识别出52个房内折返性心动过速环路,其中48个被作为射频消融靶点。每个心动过速峡部平均使用13±11次灌注式射频消融,平均功率为36±8W。在采用传统导管消融治疗的先天性心脏病患者历史对照组中,每个峡部的消融灶数量更多(23±11个),平均功率更低(27±14W)。45例房内折返性心动过速获得急性成功(占靶向心动过速的94%,占所有心动过速的87%)。平均随访17±7个月后,36例患者中有33例(92%)无复发。5例患者(14%)发生阵发性心房颤动。
包括电解剖标测和导管灌注在内的现代技术相结合,能够安全、高效地消融先天性心脏病手术修复患者的房内折返性心动过速。