Collins K K, Love B A, Walsh E P, Saul J P, Epstein M R, Triedman J K
Department of Cardiology, Children's Hospital, Boston, Massachusetts 02115, USA.
Am J Cardiol. 2000 Nov 1;86(9):969-74. doi: 10.1016/s0002-9149(00)01132-2.
Intraatrial reentrant tachycardia (IART) is common after surgery for congenital heart disease (CHD). Radiofrequency (RF) catheter ablation of IART targets anatomic areas critical to the maintenance of the arrhythmia circuit, areas that have not been well defined in this patient population. The purpose of this study was to determine the anatomic areas critical to IART circuits, defined by activation mapping and confirmed by an acutely successful RF ablation at the site. A total of 110 RF ablation procedures in 88 patients (median age 23.4 years, range 0.1 to 62.7) with CHD were reviewed. Patients were grouped according to surgical intervention: Mustard/Senning (n = 15), other biventricular repaired CHD (n = 24), Fontan (n = 43), and palliated CHD (n = 6). In first-time ablation procedures, > or = 1 IART circuits were acutely terminated in 80% of Mustard/Senning, 71% of repaired CHD, and 72% of Fontan (p = NS). The palliated CHD group underwent 1 of 6 successful procedures (17%), and this patient was excluded. The locations of acutely successful RF applications in Mustard/Senning patients (n = 14 sites) were at the tricuspid valve isthmus (57%) and at the lateral right atrial wall (43%). In patients with repaired CHD (n = 18 sites), successful RF sites were at the isthmus (67%) and the lateral (22%) and anterior (11%) right atria. In the Fontan group (n = 40 sites), successful RF sites included the lateral right atrial wall (53%), the anterior right atrium (25%), the isthmus area (15%), and the atrial septum (7%). Location of success was statistically different for the Fontan group (p = .002). In conclusion, the tricuspid valve isthmus is a critical area for ablation of IART during the Mustard/ Senning procedure and in patients with repaired CHD. IART circuits in Fontan patients are anatomically distinct, with the lateral right atrial wall being the more common area for successful RF applications. This information may guide RF and/or surgical ablation procedures in patients with CHD and IART.
房间内折返性心动过速(IART)在先天性心脏病(CHD)手术后很常见。IART的射频(RF)导管消融针对维持心律失常环路至关重要的解剖区域,而这些区域在该患者群体中尚未得到很好的界定。本研究的目的是确定IART环路至关重要的解剖区域,通过激动标测定义,并通过在该部位进行的急性成功射频消融得到证实。回顾了88例CHD患者(中位年龄23.4岁,范围0.1至62.7岁)的110次射频消融手术。患者根据手术干预进行分组:Mustard/Senning手术(n = 15)、其他双心室修复的CHD(n = 24)、Fontan手术(n = 43)和姑息性CHD(n = 6)。在首次消融手术中,80%的Mustard/Senning手术患者、71%的修复CHD患者和72%的Fontan手术患者中,≥1个IART环路被急性终止(p = 无显著性差异)。姑息性CHD组6例手术中有1例成功(17%),该患者被排除。Mustard/Senning手术患者(n = 14个部位)急性成功射频应用的位置在三尖瓣峡部(57%)和右心房侧壁(43%)。在修复CHD的患者(n = 18个部位)中,成功的射频部位在峡部(67%)、右心房外侧(22%)和前部(11%)。在Fontan组(n = 40个部位)中,成功的射频部位包括右心房侧壁(53%)、右心房前部(25%)、峡部区域(15%)和房间隔(7%)。Fontan组成功位置在统计学上有差异(p = 0.002)。总之,三尖瓣峡部是Mustard/Senning手术期间及修复CHD患者IART消融的关键区域。Fontan手术患者的IART环路在解剖学上不同,右心房侧壁是成功射频应用更常见的区域。这些信息可能指导CHD和IART患者的射频和/或手术消融程序。