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[糖尿病母亲的婴儿出生时出现上肢坏疽]

[Upper extremity gangrene in an infant of a diabetic mother, presenting at birth].

作者信息

Vakrilova L, Popivanova A, Emilova Z, Slŭncheva B, Shishkova R

出版信息

Akush Ginekol (Sofiia). 2005;44(1):47-50.

Abstract

In utero gangrene of an extremity because of an arterial thrombosis is rare. More than 20% of the reported cases concern infants of diabetic mothers (IDM) with poor control of diabetes. Changes in coagulation related to deviation of clotting factors and low plasminogen activity may be the cause. We report a case of an IDM who presented at birth with upper extremity gangrene. The Dopplersonography has shown missing pulsations and thrombosis of a. brachialis sin, which was confirmed after amputation of the arm on the 5th day. The postoperative period was complicated by septicaemia, necrotising enterocolitis and disseminated intravasal coagulation resulting in the baby's death 10 days after birth.

摘要

因动脉血栓形成导致的胎儿期肢体坏疽较为罕见。超过20%的报道病例涉及糖尿病控制不佳的糖尿病母亲所生婴儿(IDM)。与凝血因子偏差和低纤溶酶原活性相关的凝血变化可能是病因。我们报告一例IDM,出生时即出现上肢坏疽。多普勒超声显示肱动脉搏动消失及血栓形成,在出生后第5天截肢后得到证实。术后出现败血症、坏死性小肠结肠炎和弥散性血管内凝血等并发症,导致婴儿在出生后10天死亡。

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