Gangemi Aldo, Catenacci Carola, Battaglia Massimo
Laboratory for Applied Ontology, ISTC-CNR, Rome, Italy.
Stud Health Technol Inform. 2004;102:64-80.
Formal ontology has proved to be an extremely useful tool for negotiating intended meaning, for building explicit, formal data sheets, and for the discovery of novel views on existing data structures. This paper describes an example of application of formal ontological methods to the creation of biomedical ontologies. Addressed here is the ambiguous notion of inflammation, which spans across multiple linguistic meanings, multiple layers of reality, and multiple details of granularity. We use UML class diagrams, description logics, and the DOLCE foundational ontology, augmented with the Description and Situation theory, in order to provide the representational and ontological primitives that are necessary for the development of detailed, flexible, and functional biomedical ontologies. An ontology design pattern is proposed as a modelling template for inflammations.
形式本体已被证明是一种极其有用的工具，可用于协商预期含义、构建明确的形式数据表以及发现对现有数据结构的新颖观点。本文描述了将形式本体方法应用于创建生物医学本体的一个示例。这里讨论的是炎症这一模糊概念，它跨越了多种语言含义、多个现实层面和多个粒度细节。我们使用UML类图、描述逻辑以及DOLCE基础本体，并辅以描述和情境理论，以便提供开发详细、灵活且实用的生物医学本体所需的表示和本体原语。提出了一种本体设计模式作为炎症的建模模板。
